Methylation-Associated Silencing of theNuclear Receptor 1I2Gene in Advanced-Type Neuroblastomas, Identified by Bacterial Artificial Chromosome Array-Based Methylated CpG Island Amplification

Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment.

1993 • 2,242 citations

Neuroblastoma: biological insights into a clinical enigma

2003 • 2,087 citations

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

1997 • 1,960 citations

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

1998 • 1,497 citations

SXR, a novel steroid and xenobioticsensing nuclear receptor

1998 • 903 citations

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

2001 • 830 citations

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

2000 • 799 citations

Humanized xenobiotic response in mice expressing nuclear receptor SXR

2000 • 655 citations

Detection and interpretation of altered methylation patterns in cancer cells

2005 • 482 citations

Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification.

1999 • 475 citations

PPM1D is a potential target for 17q gain in neuroblastoma.

2003 • 228 citations

CpG Island Methylator Phenotype Is a Strong Determinant of Poor Prognosis in Neuroblastomas

2005 • 204 citations

PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators

2004 • 198 citations

Genetic parameters of neuroblastomas

2002 • 172 citations

Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3

2005 • 160 citations

Frequent Silencing of Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B ) Expression by Genetic and Epigenetic Mechanisms in Esophageal Squamous Cell Carcinoma

2004 • 138 citations

Silencing effect of CpG island hypermethylation and histone modifications on O6-methylguanine-DNA methyltransferase (MGMT) gene expression in human cancer

2004 • 137 citations

RASSF1A promoter region CpG island hypermethylation in phaeochromocytomas and neuroblastoma tumours

2001 • 137 citations

Nuclear receptors in cell life and death

2001 • 133 citations

Comparative genomic hybridization (CGH)‐arrays pave the way for identification of novel cancer‐related genes

2004 • 122 citations

Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma.

2003 • 109 citations

COMPARATIVE GENOMIC HYBRIDIZATION (CGH) ANALYSIS OF NEUROBLASTOMAS—AN IMPORTANT METHODOLOGICAL APPROACH IN PAEDIATRIC TUMOUR PATHOLOGY

1997 • 106 citations

Overexpression of PDZK1 within the 1q12-q22 Amplicon Is Likely To Be Associated with Drug-Resistance Phenotype in Multiple Myeloma

2004 • 94 citations

Aberrant methylation of multiple genes in neuroblastic tumours

2003 • 66 citations

Vitamin D Receptor and p21/WAF1 Are Targets of Genistein and 1,25-Dihydroxyvitamin D3 in Human Prostate Cancer Cells

2004 • 64 citations

Methylation-Associated Silencing of the Heat Shock Protein 47 Gene in Human Neuroblastoma

2004 • 39 citations

Hypermethylation‐mediated regulation of CD44 gene expression in human neuroblastoma

2002 • 39 citations

Human homologue of a candidate for the Mom1 locus, the secretory type II phospholipase A2 (PLA2S-II), maps to 1p35-36.1/D1S199.

1995 • 25 citations

The first intron of the murine β-casein gene contains a functional promoter

2003 • 20 citations

Loss of heterozygosity in Neuroblastomas—an Overview

1997 • 20 citations

Lack of phospholipase A2 mutations in neuroblastoma, melanoma and colon-cancer cell lines

1997 • 18 citations

Treatment of Localized Neuroblastoma

1986 • 14 citations