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A method for purifying the platelet membrane glycoprotein IIb-IIIa complex

Data up to Jan 2025

Published1985
Citations121
References28

Total Citations Per Year

Abstract

References (28)

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Silver staining of proteins in polyacrylamide gels

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A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa.

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Molecular Defects in Interactions of Platelets with the Vessel Wall

1984 • 381 citations

Subfractionation of human high density lipoproteins by heparin-Sepharose affinity chromatography.

1980 • 349 citations

Purification of glycoproteins IIb and III from human platelet plasma membranes and characterization of a calcium-dependent glycoprotein IIb-III complex.

1982 • 337 citations

Interaction of AP-2, a monoclonal antibody specific for the human platelet glycoprotein IIb-IIIa complex, with intact platelets.

1983 • 315 citations

The formation of Ca++-dependent complexes of platelet membrane glycoproteins IIb and IIIa in solution as determined by crossed immunoelectrophoresis

1981 • 261 citations

Identification of two structurally and functionally distinct sites on human platelet membrane glycoprotein IIb-IIIa using monoclonal antibodies.

1983 • 241 citations

Isolation and Quantitation of the Platelet Membrane Glycoprotein Deficient in Thrombasthenia Using a Monoclonal Hybridoma Antibody

1980 • 209 citations

Structure of human platelet membrane glycoproteins IIb and IIIa as determined by electron microscopy.

1985 • 194 citations

Calcium-dependent proteolysis occurs during platelet aggregation.

1983 • 185 citations

Calcium regulation of the platelet membrane glycoprotein IIb-IIIa complex.

1985 • 178 citations

Thrombasthenia

1964 • 160 citations

Isolation of the membrane glycoproteins of human blood platelets by lectin affinity chromatography

1977 • 133 citations

Evidence for calcium-sensitive structure in platelet thrombospondin. Isolation and partial characterization of thrombospondin in the presence of calcium.

1982 • 132 citations

Molecular and chemical characterization of membrane receptors

1984 • 123 citations

Polymerization and organization of actin filaments within platelets.

1983 • 92 citations

Isolation, purification, and partial characterization of platelet membrane glycoproteins IIb and IIIa.

1981 • 84 citations

The effects of organic nitrates on prostacyclin biosynthesis and platelet function in humans.

1984 • 66 citations

Platelet membrane glycoprotein IIb-IIIa complex incorporated into phospholipid vesicles. Preparation and morphology.

1985 • 60 citations

Dissociation of the glycoprotein IIb-IIIa complex in isolated human platelet membranes

1982 • 50 citations

Isolation of human platelet glycoproteins

1979 • 28 citations

Purification of human platelet membrane glycoproteins IIb and IIIa using high-performance liquid chromatography gel filtration

1983 • 21 citations

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A method for purifying the platelet membrane glycoprotein IIb-IIIa complex (1985) – Analytical Biochemistry | Metascience Observatory Explorer