Lymphokine-activated killer cells and aging in mice: Significance for defining the precursor cell

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

1982 • 2,228 citations

Natural cytotoxic reactivity of mouse lymphoid cells against syngeneic and allogeneic tumors. I. Distribution of reactivity and specificity

1975 • 1,308 citations

A glycolipid on the surface of mouse natural killer cells

1980 • 539 citations

Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells

1983 • 477 citations

Lymphokine-activated killer cell phenomenon. III. Evidence that IL-2 is sufficient for direct activation of peripheral blood lymphocytes into lymphokine-activated killer cells.

1983 • 355 citations

Lymphokine-activated killer cells: lysis of fresh syngeneic natural killer-resistant murine tumor cells by lymphocytes cultured in interleukin 2.

1984 • 299 citations

Leu-11+ lymphocytes with natural killer (NK) activity are precursors of recombinant interleukin 2 (rIL 2)-induced activated killer (AK) cells.

1985 • 263 citations

Identification of ganglio-N-tetraosylceramide as a new cell surface marker for murine natural killer (NK) cells.

1980 • 220 citations

Natural killer (NK) cells as a responder to interleukin 2 (IL 2). I. Proliferative response and establishment of cloned cells.

1983 • 196 citations

Interleukin 2-activated human killer cells are derived from phenotypically heterogeneous precursors.

1986 • 166 citations

Studies of murine large granular lymphocytes. I. Identification as effector cells in NK and K cytotoxicities.

1982 • 135 citations

Studies of human natural killer cells. I. in vivo parameters affecting normal cytotoxic function

1982 • 130 citations

Murine lymphokine-activated killer (LAK) cells: phenotypic characterization of the precursor and effector cells.

1986 • 108 citations

Studies of murine large granular lymphocytes. II. Tissue, strain, and age distributions of LGL and LAL.

1982 • 84 citations

Quantification of natural cytotoxicity by human lymphocyte subpopulations isolated by density: Heterogeneity of the effector cells

1983 • 76 citations

Suppression of alloimmune cytotoxic T lymphocyte (CTL) generation by depletion of NK cells and restoration by interferon and/or interleukin 2.

1985 • 65 citations

Generation of cytotoxic cells from murine bone marrow by human recombinant IL 2.

1986 • 60 citations

Generation of nonspecific murine cytotoxic T cells in vitro by purified human interleukin 2

1984 • 60 citations

Age-associated decline in natural killer (NK) activity reflects primarily a defect in function of NK cells

1985 • 32 citations

Rapid kinetics of lysis in human natural cell-mediated cytotoxicity: Some implications

1983 • 18 citations

Studies on the mechanism of low natural killer cell activity in infant and aged mice.

1986 • 14 citations

Heterogeneity of Cell Populations from Human Peripheral Blood Mediating Lymphokine-Stimulated Cytotoxicity

2015 • 7 citations

Stimulation of murine lymphocytes (NK cells and T cells) by human recombinant interleukin-2 (IL-2)

1984 • 4 citations