The role of interleukin-6 in lipopolysaccharide-induced weight loss, hypoglycemia and fibrinogen production, in vivo

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

1985 • 1,125 citations

Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation.

1988 • 745 citations

Evidence for the involvement of interleukin 6 in experimental cancer cachexia.

1992 • 648 citations

Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output.

1992 • 493 citations

IL-6 modulates the synthesis of a specific set of acute phase plasma proteins in vivo.

1989 • 307 citations

Metabolic Response to Infection

1975 • 300 citations

Multiple effects of tumor necrosis factor on lipoprotein lipase in vivo.

1987 • 240 citations

The metabolic effects of tumor necrosis factor and other cytokines

1991 • 200 citations

Mechanisms of Cancer Cachexia

1991 • 172 citations

Role of interleukin 6 (IL-6) in protection from lethal irradiation and in endocrine responses to IL-1 and tumor necrosis factor.

1992 • 126 citations

Hypertriglyceridemia Produced by Endotoxin: Role of Impaired Triglyceride Disposal Mechanisms

1976 • 111 citations

Protective effect of anti‐interleukin (IL)‐6 antibody against endotoxin, associated with paradoxically increased IL‐6 levels

1992 • 105 citations

BCG-induced enhancement of endotoxin sensitivity in C3H/HeJ mice. I. In vivo studies.

1980 • 100 citations

Gram-Negative Infection Increases Noninsulin-Mediated Glucose Disposal*

1991 • 76 citations

Interleukin-1 and interleukin-6 act synergistically to stimulate the release of adrenocorticotropic hormone in vivo.

1991 • 75 citations

Roles of interleukin-1 and tumor necrosis factor in lipopolysaccharide-induced hypoglycemia

1991 • 45 citations

Murine anti-human IL-6 monoclonal antibody prolongs the half-life in circulating blood and thus prolongs the bioactivity of human IL-6 in mice.

1991 • 41 citations

Differential inhibition of lipopolysaccharide-induced phenomena by anti-tumor necrosis factor alpha antibody

1990 • 31 citations

Regulation of murine mononuclear phagocyte inflammatory products by macrophage colony-stimulating factor. Lack of IL-1 and prostaglandin E2 production and generation of a specific IL-1 inhibitor.

1991 • 23 citations