Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Bone: Formation by Autoinduction

1965 • 5,498 citations

Novel Regulators of Bone Formation: Molecular Clones and Activities

1988 • 3,919 citations

Recombinant human bone morphogenetic protein induces bone formation.

1990 • 1,538 citations

Retention of differentiation potentialities during prolonged cultivation of myogenic cells.

1968 • 975 citations

Bone Cell Differentiation and Growth Factors

1983 • 877 citations

Biochemical Sequences in the Transformation of Normal Fibroblasts in Adolescent Rats

1972 • 815 citations

Transforming growth factor-beta and the initiation of chondrogenesis and osteogenesis in the rat femur.

1990 • 734 citations

Purification and characterization of other distinct bone-inducing factors.

1988 • 621 citations

In VivoStimulation of Bone Formation by Transforming Growth Factor-β

1989 • 592 citations

Construction of DNA sequences complementary to rat .alpha.1 and .alpha.2 collagen mRNA and their use in studying the regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D

1984 • 568 citations

Type beta transforming growth factor is an inhibitor of myogenic differentiation.

1986 • 559 citations

OP-1 cDNA encodes an osteogenic protein in the TGF-beta family.

1990 • 554 citations

The non-osteogenic mouse pluripotent cell line, C3H10T1/2, is induced to differentiate into osteoblastic cells by recombinant human bone morphogenetic protein-2

1990 • 498 citations

Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development.

1989 • 440 citations

Purification and Partial Amino Acid Sequence of Osteogenin, a Protein Initiating Bone Differentiation

1989 • 405 citations

Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones.

1986 • 398 citations

Bovine osteogenic protein is composed of dimers of OP-1 and BMP-2A, two members of the transforming growth factor-beta superfamily.

1990 • 377 citations

Osteocalcin. Biochemical considerations and clinical applications

1988 • 328 citations

Bone Morphogenetic Proteins

1989 • 326 citations

Localization of types I, II, and III collagen mRNAs in developing human skeletal tissues by in situ hybridization

1987 • 319 citations

Tissue specificity and developmental expression of rat osteopontin

1987 • 317 citations

Functional Properties of Hormonally Responsive Cultured Normal and Malignant Rat Osteoblastic Cells*

1981 • 278 citations

Stimulation of the expression of osteogenic and chondrogenic phenotypes in vitro by osteogenin.

1989 • 224 citations

Effects of growth factors on myogenic differentiation

1989 • 207 citations

Serum and fibroblast growth factor inhibit myogenic differentiation through a mechanism dependent on protein synthesis and independent of cell proliferation.

1986 • 196 citations

Type β transforming growth factor (TGFβ) regulation of alkaline phosphatase expression and other phenotype‐related mRNAs in osteoblastic rat osteosarcoma cells

1987 • 196 citations

Gene expression during osteogenic differentiation in mandibular condyles in vitro.

1990 • 177 citations

Vgr-1, a mammalian gene related to Xenopus Vg-1, is a member of the transforming growth factor beta gene superfamily.

1989 • 176 citations

Type-β transforming growth factor inhibits proliferation and expression of alkaline phosphatase in murine osteoblast-like cells

1986 • 167 citations

Purification and characterization of a unique osteoinductive factor from bovine bone

1989 • 159 citations

In VivoDistribution of Parathyroid Hormone Receptors in Bone: Evidence that a Predominant Osseous Target Cell Is Not the Mature Osteoblast*

1988 • 156 citations

Clonal osteogenic cell lines express myogenic and adipocytic developmental potential

1991 • 137 citations

Developmental appearance of Gla proteins (osteocalcin) and alkaline phosphatase in tooth germs and bones of the rat.

1987 • 122 citations

cDNA cloning of alkaline phosphatase from rat osteosarcoma (ROS 17/2.8) cells

1987 • 107 citations

Osteogenin inhibits proliferation and stimulates differentiation in mouse osteoblast-like cells (MC3T3-E1)

1990 • 80 citations

Bone Morphogenetic Protein-induced Cartilage Development in Tissue Culture

1984 • 80 citations

Analysis of cartilage differentiation from skeletal muscle grown on bone matrix

1980 • 64 citations

Transforming growth factor-β reduces the phenotypic expression of osteoblastic MP3T3-E1 cells in monolayer culture

1987 • 60 citations

A substratum of bone matrix for differentiation of mesenchymal cells into chondro-osseous tissues in vitro

1970 • 49 citations

Identification of the promoter and first exon of the mouse alpha 1 (III) collagen gene.

1985 • 44 citations

Analysis of cartilage differentiation from skeletal muscle grown on bone matrix

1980 • 35 citations

Transforming growth factor β enhances parathyroid hormone stimulation of adenylate cyclase in clonal osteoblast‐like cells

1990 • 17 citations