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Hypolipidemic effects in dogs of ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase

Data up to Jan 2025

Published1979
Citations110
References25

Total Citations Per Year

Abstract

References (25)

PLASMA-HIGH-DENSITY-LIPOPROTEIN CONCENTRATION AND DEVELOPMENT OF ISCHÆMIC HEART-DISEASE

1975 • 2,653 citations

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ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.

1976 • 926 citations

Quantitative isolation and gas–liquid chromatographic analysis of total fecal bile acids

1965 • 891 citations

Competitive inhibition of 3‐hydroxy‐3‐methylglutaryl coenzyme a reductase by ML‐236A and ML‐236B fungal metabolites, having hypocholesterolemic activity

1976 • 788 citations

Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase

1978 • 556 citations

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1964 • 298 citations

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1976 • 275 citations

The removal of cholesterol from aortic smooth muscle cells in culture and landschutz ascites cells by fractions of human high-density apolipoprotein

1975 • 264 citations

Inhibition of Cholesterol Synthesis in vitro and in vivo by ML‐236A and ML‐236B, Competitive Inhibitors of 3‐Hydroxy‐3‐methylglutaryl‐Coenzyme A Reductase

1977 • 261 citations

Inhibitory Effects on Lipid Metabolismn in Cultured Cells of ML‐236B, a Potent Inhibitor of 3‐Hydroxt‐3‐methylglutaryl‐Cornzyme‐A Reductase

1978 • 252 citations

Plasma cholesterol lowering action of bile acid binding polymers in experimental animals

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1966 • 103 citations

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1972 • 102 citations

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1974 • 100 citations

Mechanism for elevation of hepatic cholesterol synthesis and serum cholesterol levels in triton WR-1339-induced hyperlipidemia

1977 • 89 citations

Concentration of lipoproteins containing apolipoprotein B in human peripheral lymph

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Cholestyramine in Dogs

1965 • 19 citations

Effects of colestipol hydrochloride (U-26,597A) on serum and fecal lipids in dogs

1973 • 18 citations

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Hypolipidemic effects in dogs of ML-236B, a competitive inhibitor of… (1979) – Atherosclerosis | Metascience Observatory Explorer