Effects of glycosylation on protein function

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

1990 • 1,756 citations

GLYCOBIOLOGY

1988 • 1,107 citations

Glycoproteins: what are the sugar chains for?

1989 • 459 citations

The role of carbohydrate in recombinant human erythropoietin

1990 • 236 citations

Tissue-specific N-glycosylation, site-specific oligosaccharide patterns and lentil lectin recognition of rat Thy-1.

1987 • 218 citations

Glycosylation of recombinant protein therapeutics: control and functional implications

1991 • 205 citations

Role of carbohydrates in glycoprotein hormone signal transduction

1989 • 197 citations

Role of sugar chains in the in vitro biological activity of human erythropoietin produced in recombinant Chinese hamster ovary cells.

1990 • 140 citations

Biological Activity and Metabolic Clearance of a Recombinant Human Thyrotropin Produced in Chinese Hamster Ovary Cells

1991 • 135 citations

Current ideas on the significance of protein glycosylation

1986 • 108 citations

In Vitroandin VivoBioactivity of Recombinant Human Follicle-Stimulating Hormone and Partially Deglycosylated Variants Secreted by Transfected Eukaryotic Cell Lines*

1990 • 106 citations

IgE-Binding Factors and Regulation of the IgE Antibody Response

1988 • 100 citations

A biological role of the carbohydrate moieties of laminin.

1990 • 100 citations

The sialylated oligosaccharides of recombinant bovine lutropin modulate hormone bioactivity.

1990 • 97 citations

Intracellular transport of soluble and membrane-bound glycoproteins: folding, assembly and secretion of anchor-free influenza hemagglutinin.

1990 • 97 citations

Physicochemical and biological characterization of asialoerythropoietin

1990 • 93 citations

Glycosylation at Asn-184 inhibits the conversion of single-chain to two-chain tissue-type plasminogen activator by plasmin

1990 • 63 citations

Spatial structures of glycan chains of glycoproteins in relation to metabolism and function. Survey of a decade of research

1984 • 47 citations

N-linked oligosaccharides on free alpha interfere with its ability to combine with human chorionic gonadotropin-beta subunit.

1990 • 37 citations

Differential interactions of human choriogonadotropin and its antagonistic aglycosylated analog with their receptor.

1990 • 25 citations

Altered glycosylation of human chorionic gonadotropin decreases its hormonal activity as determined by cyclic-adenosine 3',5'-monophosphate production in MA-10 cells

1990 • 22 citations

Effect of glycosylation on the conformational epitopes of the glycoprotein of vesicular stomatitis virus (New Jersey serotype)

1991 • 19 citations

Intrinsic tryptophan fluorescence measurements suggest that polylactosaminyl glycosylation affects the protein conformation of the gelatin‐binding domain from human placental fibronectin

1990 • 10 citations