Selective cloning and sequence analysis of the human L1 (LINE-1) sequences which transposed in the relatively recent past

Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase

1988 • 17,059 citations

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

CpG Islands in vertebrate genomes

1987 • 3,315 citations

Dideoxy sequencing method using denatured plasmid templates

1986 • 1,537 citations

DNA methylation and the frequency of CpG in animal DNA

1980 • 1,146 citations

Haemophilia A resulting from de novo insertion of L1 sequences represents a novel mechanism for mutation in man

1988 • 883 citations

Origins and Evolutionary Relationships of Retroviruses

1989 • 581 citations

The Origin and Evolution of Retroposons

1985 • 555 citations

Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene

1987 • 516 citations

Sequence homology between retroviral reverse transcriptase and putative polymerases of hepatitis B virus and cauliflower mosaic virus

1983 • 464 citations

The sequence of a large L1Md element reveals a tandemly repeated 5' end and several features found in retrotransposons.

1986 • 326 citations

Origin of the human L1 elements: Proposed progenitor genes deduced from a consensus DNA sequence

1987 • 312 citations

Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro

1988 • 300 citations

Unit-length line-1 transcripts in human teratocarcinoma cells.

1988 • 296 citations

Sp1 binds to promoter sequences and activates herpes simplex virus ‘immediate-early’ gene transcription in vitro

1985 • 289 citations

Transposable elements controlling I-R hybrid dysgenesis in D. melanogaster are similar to mammalian LINEs

1986 • 239 citations

LINE-1: A mammalian transposable element

1987 • 224 citations

L1 family of repetitive DNA sequences in primates may be derived from a sequence encoding a reverse transcriptase-related protein

1986 • 218 citations

Cin4, an insert altering the structure of the A1 gene in Zea mays , exhibits properties of nonviral retrotransposons

1987 • 193 citations

Ingi, a 5.2-kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian LINEs.

1987 • 182 citations

A family of long reiterated DNA sequences, one copy of which is next to the human beta globin gene

1980 • 168 citations

jockey, a mobile drosophila element similar to mammalian LINEs, is transcribed from the internal promoter by RNA polymerase II

1988 • 165 citations

Expression of a cytoplasmic LINE-1 transcript is regulated in a human teratocarcinoma cell line.

1985 • 164 citations

Close structural resemblance between putative polymerase of a Drosophila transposable genetic element 17.6 and pol gene product of Moloney murine leukaemia virus.

1985 • 159 citations

Functional expression of a sequence-specific endonuclease encoded by the retrotransposon R2Bm

1988 • 150 citations

Conservation throughout mammalia and extensive protein-encoding capacity of the highly repeated DNA long interspersed sequence one

1986 • 147 citations

Sequence analysis of a Kpnl family member near the 3′ end of human β-globin gene

1985 • 146 citations

The Sequence of a Large L1Md Element Reveals a Tandemly Repeated 5′ End and Several Features Found in Retrotransposons

1986 • 140 citations

The Drosophila mobile element jockey belongs to LINEs and contains coding sequences homologous to some retroviral proteins

1988 • 111 citations

Structure of the highly repeated, long interspersed DNA family (LINE or L1Rn) of the rat.

1986 • 107 citations

KpnI families of long, interspersed repetitive DNAs in human and other primate genomes

1982 • 101 citations

Related polypeptides are encoded by Drosophila F elements, I factors, and mammalian L1 sequences.

1987 • 100 citations

Kpn I family of long interspersed repeated DNA sequences in primates: polymorphism of family members and evidence for transcription.

1983 • 92 citations

A promoter of the rat insulin-like growth factor II gene consists of minimal control elements

1988 • 88 citations

Characterization of a nondeleterious L1 insertion in an intron of the human factor VIII gene and further evidence of open reading frames in functional L1 elements

1989 • 69 citations

The Abundant LINE-1 Family of Repeated DNA Sequences in Mammals: Genes and Pseudogenes

1986 • 64 citations

Members of the Kpnl family of long interspersed repeated sequences join and interrupt α-satellite in the monkey genome

1983 • 64 citations

GENAS: a database system for nucleic add sequence analysis

1984 • 60 citations

Ingi, a 5.2-kb Dispersed Sequence Element from Trypanosoma brucei That Carries Half of a Smaller Mobile Element at Either End and Has Homology with Mammalian LINEs

1987 • 55 citations

The structure of the regulatory region of the rat L1 (L1Rn, long interspersed repeated) DNA family of transposable elements

1988 • 54 citations

Genomic representation of the Hind II 1.9 kb repeated DNA

1982 • 47 citations

A novel procedure for selective cloning ofNotI linking fragments from mammalian genomes

1988 • 23 citations

The L1 family (Kpnl family) sequence near the 3' end of human β-globin gene may have been derived from an active L1 sequence

1987 • 15 citations

Two-dimensional gel electrophoretic analysis of the HindIII 1.8-kb repetitive-sequence family in the human genome

1983 • 12 citations

RNA-mediated (?) dispersion of the L1 family of long interspersed repetitive DNA in mammalian genomes.

1987 • 4 citations