Activation of the medial septal area attenuates LTP of the lateral perforant path and enhances heterosynaptic LTD of the medial perforant path in aged rats

The organization of behavior

1988 • 8,668 citations

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

The organization of behavior.

1950 • 6,879 citations

The Cholinergic Hypothesis of Geriatric Memory Dysfunction

1982 • 5,422 citations

Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat.

1979 • 1,970 citations

GABA-containing neurons in the septum control inhibitory interneurons in the hippocampus

1988 • 1,247 citations

Long-Term Depression

1989 • 1,151 citations

Impaired Long-Term Potentiation, Spatial Learning, and Hippocampal Development in fyn Mutant Mice

1992 • 1,138 citations

Organization of Behavior.

1950 • 1,082 citations

The Biochemistry of Memory: A New and Specific Hypothesis

1984 • 1,048 citations

An analysis of the origins of the cholinergic and noncholinergic septal projections to the hippocampal formation of the rat

1985 • 676 citations

Origin and termination of the hippocampal perforant path in the rat studied by silver impregnation

1972 • 662 citations

Synapses as associative memory elements in the hippocampal formation

1979 • 573 citations

The NMDA receptor antagonist D-2-amino-5-phosphonopentanoate (D-AP5) impairs spatial learning and LTP in vivo at intracerebral concentrations comparable to those that block LTP in vitro

1992 • 545 citations

Comparative effects of cholinergic drugs and lesions of nucleus basalis or fimbria-fornix on delayed matching in rats

1985 • 493 citations

The effects of hippocampal lesions upon spatial and non-spatial tests of working memory

1986 • 489 citations

Projection of the lateral part of the entorhinal area to the hippocampus and fascia dentata

1972 • 482 citations

Confirmation from choline acetylase analyses of a massive cholinergic innervation to the rat hippocampus

1967 • 469 citations

Cortical projection patterns of the medial septum‐diagonal band complex

1990 • 387 citations

Lesions in nucleus basalis magnocellularis and medial septal area of rats produce qualitatively similar memory impairments

1985 • 386 citations

The opioid peptide dynorphin mediates heterosynaptic depression of hippocampal mossy fibre synapses and modulates long-term potentiation

1993 • 342 citations

An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses.

1985 • 334 citations

Evidence for two physiologically distinct perforant pathways to the fascia dentata

1980 • 332 citations

The effects of aging on hippocampal and cortical projections of the forebrain cholinergic system

1987 • 318 citations

Physiological identification and analysis of dentate granule cell responses to stimulation of the medial and lateral perforant pathways in the rat

1977 • 283 citations

Endogenous dynorphins inhibit excitatory neurotransmission and block LTP induction in the hippocampus

1993 • 279 citations

Cholinergic and GABAergic modulation of medial septal area: Effect on working memory.

1990 • 277 citations

An age comparison of the rates of acquisition and forgetting of spatial information in relation to long-term enhancement of hippocampal synapses.

1985 • 275 citations

Maintenance of long-term potentiation in rat dentate gyrus requires protein synthesis but not messenger RNA synthesis immediately post-tetanization

1989 • 275 citations

Neuronal transmission through hippocampal pathways dependent on behavior

1978 • 264 citations

Changes in acetylcholinesterase and distribution of degenerating fibres in the hippocampal region after septal lesions in the rat

1973 • 264 citations

Cholinergic and GABAergic modulation of medial septal area: Effect on working memory.

1990 • 263 citations

Characteristics of hippocampal primed burst potentiation in vitro and in the awake rat

1988 • 212 citations

Muscarinic receptor activation facilitates the induction of long-term potentiation (LTP) in the rat dentate gyrus

1990 • 187 citations

Priming of associative long-term depression in the dentate gyrus by θ frequency synaptic activity

1992 • 177 citations

Septo-hippocampal and other medial septum-diagonal band neurons: electrophysiological and pharmacological properties

1984 • 168 citations

Correlation between the induction of an immediate early gene,zif/268, and long-term potentiation in the dentate gyrus

1992 • 168 citations

Effect on memory processing by D-cycloserine, an agonist of the NMDA/glycine receptor

1992 • 154 citations

Synaptic plasticity in the hippocampus is modulated by behavioral state

1989 • 152 citations

Anatomical and Functional Aspects of the Septo‐Hippocampal Projections

1978 • 149 citations

Muscimol injections in the medial septum impair spatial learning

1990 • 147 citations

Muscarinic Depression of Long-Term Potentiation in CA3 Hippocampal Neurons

1988 • 146 citations

Induction of long-term potentiation at hippocampal mossy-fiber synapses follows a Hebbian rule

1990 • 145 citations

Medial septal facilitation of hippocampal granule cell activity is mediated by inhibition of inhibitory interneurones

1985 • 144 citations

Effect of anticholinergic drug on long-term potentiation in rat hippocampal slices

1989 • 108 citations

The role of NMDA receptors in long-term potentiation (LTP) and depression (LTD) in rat visual cortex

1991 • 106 citations

Distribution of glutamate‐decarboxylase‐immunoreactive neurons and synapses in the rat and monkey hippocampus: Light and electron microscopy

1988 • 106 citations

Neurotransmitters, neuroreceptors and aging

1991 • 94 citations

Commissural synapses, but not mossy fiber synapses, in hippocampal field CA3 exhibit associative long-term potentiation and depression

1989 • 92 citations

Modulation of long-term potentiation by peripherally administered amphetamine and epinephrine

1984 • 92 citations

NMDA‐dependent heterosynaptic long‐term depression in the dentate gyrus of anaesthetized rats

1992 • 89 citations

Opioid-mediated facilitation of long-term potentiation at the lateral perforant path-dentate granule cell synapse.

1991 • 89 citations

Long‐term Potentiation and Field EPSPs in the Lateral and Medial Perforant Paths in the Dentate Gyrus In Vitro: a Comparison

1992 • 88 citations

Opioid receptors are involved in an NMDA receptor-independent mechanism of LTP induction at hippocampal mossy fiber-CA3 synapses

1991 • 81 citations

Linear relation between the magnitude of long-term potentiation in the dentate gyrus and associative learning in the rat. A demonstration using commissural inhibition and local infusion of an N-methyl-d-aspartate receptor antagonist

1989 • 79 citations

δ Opioid receptor activation is required to induce LTP of synaptic transmission in the lateral perforant path in vivo

1991 • 77 citations

Pre‐ and post‐synaptic cholinergic dysfunction in aged rodent brain regions: New findings and an interpretative review

1990 • 75 citations

Chronically elevating plasma Mg2+ improves hippocampal frequency potentiation and reversal learning in aged and young rats

1984 • 75 citations

Induction of long-term depression and potentiation by low- and high-frequency stimulation in the dentate area of the anesthetized rat: magnitude, time course and EEG

1987 • 70 citations

Heterosynaptic long-term depression is facilitated by blockade of inhibition in area CA1 of the hippocampus

1991 • 69 citations

Activation of AP5-sensitive NMDA Receptors is Not Required to Induce LTP of Synaptic Transmission in the Lateral Perforant Path

1991 • 67 citations

Heterosynaptic interactions between septal and entorhinal inputs to the dentate gyrus: long-term potentiation effects

1982 • 65 citations

Long-term depression: not so depressing after all.

1993 • 58 citations

NMDA receptor antagonists block the induction of long-term depression in the hippocampal dentate gyrus of the anesthetized rat

1991 • 57 citations

c-fos Protooncogene expression in rat hippocampus and entorhinal cortex following tetanic stimulation of the perforant path

1991 • 51 citations

Equivalent spatial location memory deficits in rats with medial septum or hippocampal formation lesions and patients with dementia of the Alzheimer's type

1989 • 47 citations

Enhanced long-term potentiation induced in rat dentate gyrus by coactivation of septal and entorhinal inputs: Temporal constraints

1986 • 41 citations

Glycine‐Like Modulation of N‐Methyl‐<scp>d</scp>‐Aspartate Receptors by a Monoclonal Antibody That Enhances Long‐Term Potentiation

1991 • 31 citations

Evoked field responses, recurrent inhibition, long-term potentiation and immobility-related nonrhythmical EEG in the dentate gyrus of fimbria-fornix-lesioned and control rats

1991 • 22 citations

Iontophoretic study of medial septal neurons in the unanesthetized rat

1991 • 16 citations

Rhythmical bursting activity and GABAergic mechanisms in the medial septum of normal and pertussis toxin-pretreated rats

1989 • 14 citations