Cooperation between the GATA and RUNX factors Serpent and Lozenge during Drosophila hematopoiesis

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1978 • 3,910 citations

AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis

1996 • 1,885 citations

Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1

1991 • 1,321 citations

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

1996 • 1,195 citations

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

1999 • 1,091 citations

Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1.

1996 • 763 citations

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

2002 • 751 citations

FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation

1997 • 723 citations

Core-binding factors in haematopoiesis and leukaemia

2002 • 552 citations

Transcription Factor GATA-2 Is Required for Proliferation/Survival of Early Hematopoietic Cells and Mast Cell Formation, But Not for Erythroid and Myeloid Terminal Differentiation

1997 • 543 citations

Transcription Factor GATA-2 Is Required for Proliferation/Survival of Early Hematopoietic Cells and Mast Cell Formation, But Not for Erythroid and Myeloid Terminal Differentiation

1997 • 503 citations

Specification of Drosophila Hematopoietic Lineage by Conserved Transcription Factors

2000 • 475 citations

Embryonic origin of hemocytes and their relationship to cell death in Drosophila

1994 • 414 citations

Croquemort, A Novel Drosophila Hemocyte/Macrophage Receptor that Recognizes Apoptotic Cells

1996 • 394 citations

In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis

2002 • 367 citations

Failure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOG

1998 • 352 citations

Consequences of GATA-1 Deficiency in Megakaryocytes and Platelets

1999 • 327 citations

RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation

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A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila

1996 • 310 citations

Peroxidasin: a novel enzyme-matrix protein of Drosophila development.

1994 • 285 citations

Hematopoiesis and stem cells: plasticity versus developmental heterogeneity

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Enforced Expression of the GATA-2 Transcription Factor Blocks Normal Hematopoiesis

1999 • 239 citations

Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains

1999 • 225 citations

A Serrate-expressing signaling center controlsDrosophilahematopoiesis

2003 • 222 citations

Transcriptional activity of Pannier is regulated negatively by heterodimerization of the GATA DNA-binding domain with a cofactor encoded by the u-shaped gene of Drosophila

1997 • 189 citations

A P-insertion screen identifying novel X-linked essential genes in Drosophila

2002 • 178 citations

The Mammalian Basic Helix Loop Helix Protein HES-1 Binds to and Modulates the Transactivating Function of the Runt-related Factor Cbfa1

2000 • 177 citations

Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder

2003 • 174 citations

glide/gcmIs Expressed and Required in the Scavenger Cell Lineage

1997 • 170 citations

gcm2 Promotes Glial Cell Differentiation and Is Required with glial cells missing for Macrophage Development in Drosophila

2002 • 168 citations

Control of megakaryocyte-specific gene expression by GATA-1 and FOG-1: role of Ets transcription factors

2002 • 160 citations

The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila

2001 • 158 citations

Overlapping Activators and Repressors Delimit Transcriptional Response to Receptor Tyrosine Kinase Signals in the Drosophila Eye

2000 • 157 citations

A mutant affecting the crystal cells inDrosophila melanogaster

1980 • 118 citations

Antagonism between C/EBPβ and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors

2000 • 117 citations

Two isoforms of Serpent containing either one or two GATA zinc fingers have different roles in Drosophila haematopoiesis

2002 • 100 citations

Drosophila Homologs of the Proto-Oncogene Product PEBP2/CBFβ Regulate the DNA-Binding Properties of Runt

1996 • 91 citations

Differential roles of GATA‐1 and GATA‐2 in growth and differentiation of mast cells

1998 • 91 citations

The N-terminal Zinc Finger of the Erythroid Transcription Factor GATA-1 Binds GATC Motifs in DNA

2001 • 90 citations

The serpent gene is necessary for progression through the early stages of fat-body development

1996 • 89 citations

C/EBPβ and GATA-1 Synergistically Regulate Activity of the Eosinophil Granule Major Basic Protein Promoter: Implication for C/EBPβ Activity in Eosinophil Gene Expression

1999 • 62 citations

New members of the Drosophila Myc transcription factor subfamily revealed by a genome-wide examination for basic helix-loop-helix genes

2001 • 58 citations

C/EBPβ and GATA-1 Synergistically Regulate Activity of the Eosinophil Granule Major Basic Protein Promoter: Implication for C/EBPβ Activity in Eosinophil Gene Expression

1999 • 56 citations

Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: demonstration by in situ hybridization

1996 • 52 citations

Transcriptional regulation of hematopoiesis in Drosophila

2003 • 46 citations

Redundant function of Runt Domain binding partners, Big brother and Brother, duringDrosophiladevelopment

2001 • 31 citations

The Circulatory System and Associated Tissues

1972 • 23 citations