Somatomedin-C Substitutes for Insulin for the Growth of Mammary Epithelial Cells from Normal Virgin Mice in Serum-Free Collagen Gel Cell Culture*

Methods for growth of cultured cells in serum-free medium

1980 • 1,013 citations

An improved fluorometric assay for DNA

1971 • 997 citations

Multiple hormone interactions in the developmental biology of the mammary gland.

1980 • 866 citations

Direct Demonstration of Separate Receptors for Growth and Metabolic Activities of Insulin and Multiplication-stimulating Activity (an Insulinlike Growth Factor) Using Antibodies to the Insulin Receptor

1980 • 346 citations

Demonstration of two subtypes of insulin-like growth factor receptors by affinity cross-linking.

1981 • 332 citations

Epidermal growth factor (EGF) and somatomedin C regulate G1 progression in competent BALB/c-3T3 cells

1982 • 318 citations

Somatomedin-C receptors and growth effects in human breast cells maintained in long-term tissue culture.

1984 • 256 citations

Interactions of Insulin-Like Growth Factors I and II and Multiplication-Stimulating Activity with Receptors and Serum Carrier Proteins

1980 • 254 citations

Growth-Stimulatory Actions of Insulinin Vitroandin Vivo*

1984 • 222 citations

Insulin as a Potent, Specific Growth Factor in a Rat Hepatoma Cell Line

1981 • 221 citations

Unilamellar liposomes made with the French pressure cell: a simple preparative and semiquantitative technique

1980 • 153 citations

Receptor binding and growth-promoting activity of insulin-like growth factors in human breast cancer cells (T-47D) in culture.

1984 • 139 citations

Stimulation of Mammary Epithelial Cell Growthin Vitro: Interaction of Epidermal Growth Factor and Mammogenic Hormones*

1985 • 138 citations

Serum-free growth of normal and tumor mouse mammary epithelial cells in primary culture.

1982 • 118 citations

Insulin is essential for accumulation of casein mRNA in mouse mammary epithelial cells.

1981 • 97 citations

Method for culturing mammary epithelial cells in a rat tail collagen gel matrix

1983 • 94 citations

Interaction of circulating cell‐derived and plasma growth factors in stimulating cultured smooth muscle cell replication

1984 • 93 citations

Regulation of Estrogen and Progesterone Receptor Levels in Mouse Mammary Epithelial Cells Grown in Serum-Free Collagen Gel Cultures*

1985 • 77 citations

Insulin‐like growth factor I/somatomedin‐C (IGF‐I/SM‐C) and glucocorticoids synergistically regulate mitosis in competent human fibroblasts

1983 • 70 citations

Development of Insulin-Sensitivity by Mouse Mammary Gland In Vitro

1970 • 61 citations

Insulin promotes the growth of F9 embryonal carcinoma cells apparently by acting through its own receptor

1982 • 55 citations

Mitogen-potentiating action and binding characteristics of insulin and insulin-like growth factors in Chinese hamster fibroblasts

1983 • 51 citations

Insulin receptors in murine mammary cells: Comparison in pregnant and nonpregnant animals

1974 • 45 citations

Perturbation by insulin of human breast cancer cell cycle kinetics.

1984 • 44 citations

Changes in Scatchard Plots for Insulin Binding to Mammary Epithelial Cells from Cycling, Pregnant, and Lactating Mice*

1982 • 36 citations

Partial purification and characterization of mammary stimulating factor, a protein which promotes proliferation of mammary epithelium

1979 • 32 citations

Insulin effect on the cell cycle: analysis of the kinetics of growth parameters in confluent chick cells.

1976 • 31 citations

Isolation and serum-free cultivation of mammary epithelial cells within a collagen gel matrix.

1984 • 29 citations

Transplantation of mouse mammary epithelial cells grown in primary collagen gel cultures.

1982 • 27 citations

Somatomedins (insulin-like growth factors), but not growth hormone, are mitogenic for chicken heart mesenchymal cells and act synergistically with epidermal growth factor and brain fibroblast growth factor

1984 • 27 citations

Effect of insulin at dilution endpoint concentrations on macromolecular synthesis in normal mouse mammary and human breast cancer epithelial cells

1982 • 4 citations

Insulin-like Growth Factor II Binding to Cultured Human Chondrosarcoma Cells

1985 • 2 citations