Analysis of the androgenic activity of synthetic “progestins” currently used for the treatment of prostate cancer

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Methods of Biochemical Analysis

1956 • 4,535 citations

Studies on Prostatic Cancer. I. The Effect of Castration, of Estrogen and of Androgen Injection on Serum Phosphatases in Metastatic Carcinoma of the Prostate

1941 • 3,235 citations

Extension of Multiple Range Tests to Group Means with Unequal Numbers of Replications

1956 • 3,120 citations

Polyamine metabolism and function

1982 • 1,649 citations

Important Advances in Oncology: 1986

1986 • 912 citations

ENDOCRINE CONTROL OF PROSTATIC CARCINOMA

1950 • 377 citations

Complete androgen blockade for the treatment of prostate cancer.

1985 • 282 citations

New hormonal therapy in prostatic carcinoma: combined treatment with an LHRH agonist and an antiandrogen.

1982 • 273 citations

Selective Effect of Androgens on LH and FSH Release in Anterior Pituitary Cells in Culture

1976 • 255 citations

Antiandrogenic Effect of Spirolactones: Mechanism of Action

1975 • 244 citations

Treatment of Hirsutism With Spironolactone

1982 • 234 citations

Antifertility Effects of LHRH Agonists in the Male

1980 • 197 citations

Treatment of Prostate Cancer with Gonadotropin-Releasing Hormone Agonists

1986 • 186 citations

Treatment of newly diagnosed metastatic prostate cancer patients with chemotherapy agents in combination with hormones versus hormones alone

1983 • 177 citations

Comparison of the antiandrogenic/androgenic activities of flutamide, cyproterone acetate and megestrol acetate

1985 • 157 citations

Combination therapy with flutamide and castration (LHRH agonist or orchiectomy) in advanced prostate cancer: A marked improvement in response and survival

1985 • 155 citations

Involvement of Norepinephrine in Transmission of The Stimulatory Influence of Progesterone on Gonadotropin Release11

1972 • 150 citations

A Novel Use of Spironolactone: Treatment of Hirsutism

1980 • 126 citations

Synandrogenic and Antiandrogenic Effect of Progestins: Comparison with Nonprogestational Antiandrogens¹

1974 • 123 citations

Acute Stimulatory Effects of Progesterone on Luteinizing Hormone and Follicle-Stimulating Hormone Release in Rat Anterior Pituitary Cells in Culture

1980 • 113 citations

Interaction of Digitalis and Spironolactone with Human Sex Steroid Receptors

1978 • 95 citations

Cardiovascular Complications in the Treatment of Prostatic Carcinoma

1981 • 92 citations

Reconsideration of orchiectomy in the treatment of advanced prostatic carcinoma.

1977 • 85 citations

MASCULINIZATION OF FEMALE FETUSES IN THE RAT BY PROGESTATIONAL COMPOUNDS

1960 • 83 citations

A STUDY OF THE VIRILIZING EFFECT OF PROGESTOGENS ON THE FEMALE RAT FETUS

1961 • 78 citations

Biological studies on an anti-androgen (SH 714)

1967 • 73 citations

A wide range of sensitivities to androgens develops in cloned shionogi mouse mammary tumor cells

1986 • 68 citations

ANTI-OVULATORY AND OTHER BIOLOGICAL PROPERTIES OF MEGESTROL ACETATE 17 ACETOXY-6 METHYL PREGNA 4:6-DIENE-3:20-DIONE (B.D.H. 1298)

1963 • 64 citations

Effect of Megestrol Acetate (Megace®) on Steroid Metabolism and Steroid-Protein Binding in the Human Prostate

1976 • 62 citations

New Therapeutic Approach to the Hirsute Patient

1979 • 61 citations

Reconsideration of Orchiectomy in the Treatment of Advanced Prostatic Carcinoma

1977 • 40 citations

THE STIMULATION OF MALE DUCT DERIVATIVES IN FEMALE GUINEA-PIGS WITH AN ANTIANDROGEN, CYPROTERONE ACETATE

1974 • 35 citations

Interaction of medroxyprogesterone acetate with cytosol androgen receptors in the rat hypothalamus and pituitary

1983 • 32 citations

High Inhibitory Activity of R 5020, A Pure Progestin, at the Hypothalamic-Adenohypophyseal Level on Gonadotropin Secretion

1977 • 32 citations

Deoxyribonucleic acid and polyamine synthesis in rat ventral prostate. Effects of age of the intact rat and androgen stimulation of the castrated rat with testosterone, 5α-dihydrotestosterone and 5α-androstane-3β, 17β-diol

1977 • 31 citations

Stimulative effect of physiological doses of androgen or pharmacological doses of estrogen on growth of Shionogi carcinoma 115 in mice.

1985 • 25 citations

SC 25152: a potent mineralocorticoid antagonist with decreased antiandrogenic activity relative to spironolactone.

1979 • 9 citations

Ornithine decarboxylase activity during neonatal development of the rat ventral prostate

1977 • 7 citations