The adaptor protein p40phox as a positive regulator of the superoxide-producing phagocyte oxidase

NADPH Oxidase: An Update

1999 • 2,134 citations

Identification of a Family of Muscarinic Acetylcholine Receptor Genes

1987 • 1,439 citations

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

2001 • 600 citations

Chemoattractant signaling and leukocyte activation

1995 • 510 citations

Mutations in the X-linked and autosomal recessive forms of chronic granulomatous disease

1996 • 424 citations

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

2001 • 402 citations

Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558.

1991 • 379 citations

Activation of NADPH-dependent superoxide production in a cell-free system by sodium dodecyl sulfate.

1985 • 356 citations

Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3‐kinases: Binding partners of SH3 domains?

1996 • 304 citations

p40phox, a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains

1993 • 295 citations

Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.

1994 • 286 citations

Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets.

1994 • 285 citations

Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558.

1994 • 260 citations

A positive feedback loop stabilizes the guanine-nucleotide exchange factor Cdc24 at sites of polarization

2002 • 231 citations

Tetratricopeptide Repeat (TPR) Motifs of p67 Participate in Interaction with the Small GTPase Rac and Activation of the Phagocyte NADPH Oxidase

1999 • 230 citations

Mechanism for Phosphorylation-induced Activation of the Phagocyte NADPH Oxidase Protein p47

1999 • 221 citations

Novel modular domain PB1 recognizes PC motif to mediate functional protein-protein interactions

2001 • 179 citations

Phosphatidylinositol 3-phosphate is generated in phagosomal membranes

2001 • 178 citations

Activation of the Neutrophil Respiratory Burst Oxidase

1999 • 174 citations

Solution structure of the PX domain, a target of the SH3 domain.

2001 • 165 citations

Cytosolic Phox proteins interact with and regulate the assembly of coronin in neutrophils

1997 • 152 citations

Mechanisms of NADPH oxidase activation: translocation of p40phox, Rac1 and Rac2 from the cytosol to the membranes in human neutrophils lacking p47phox or p67phox

1996 • 138 citations

A Novel Cytosolic Component, p40phox, of Respiratory Burst Oxidase Associates with p67phox and Is Absent in Patients with Chronic Granulomatous Disease Who Lack p67phox

1994 • 113 citations

p40 Down-regulates NADPH Oxidase Activity through Interactions with Its SH3 Domain

1997 • 113 citations

Topology of cytochrome b558 in neutrophil membrane analyzed by anti-peptide antibodies and proteolysis.

1992 • 110 citations

p40 Is Phosphorylated on Threonine 154 and Serine 315 during Activation of the Phagocyte NADPH Oxidase

1998 • 109 citations

156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox.

1994 • 107 citations

Role of p67-phox SH3 domains in assembly of the NADPH oxidase system.

1994 • 106 citations

Point mutation in the cytoplasmic domain of the neutrophil p22-phox cytochrome b subunit is associated with a nonfunctional NADPH oxidase and chronic granulomatous disease.

1991 • 99 citations

[3] Regulation of G-protein activation by mastoparans and other cationic peptides

1994 • 97 citations

The PX Domain as a Novel Phosphoinositide- Binding Module

2001 • 94 citations

The NADPH‐Dependent Oxidase of Phagocytes

1999 • 89 citations

Purification of the 260 kDa cytosolic complex involved in the Superoxide production of guinea pig neutrophils

1993 • 83 citations

The PC motif : a novel and evolutionarily conserved sequence involved in interaction between p40 ^phox and p67^phox, SH3 domain‐containing cytosolic factors of the phagocyte NADPH oxidase

1998 • 80 citations

Interactions between the Cytosolic Components p47 and p67 of the Human Neutrophil NADPH Oxidase That Are Not Required for Activation in the Cell-free System

1995 • 78 citations

Functional modules and expression of mouse p40 ^phox and p67^phox, SH3‐domain‐containing proteins involved in the phagocyte NADPH oxidase complex

1998 • 77 citations

Structure and ligand recognition of the PB1 domain: a novel protein module binding to the PC motif

2001 • 76 citations

p40phox participates in the activation of NADPH oxidase by increasing the affinity of p47phox for flavocytochrome b558

2000 • 76 citations

Location of the Epitope for 7D5, a Monoclonal Antibody Raised against Human Flavocytochrome b₅₅₈, to the Extracellular Peptide Portion of Primate gp91^phox

2001 • 74 citations

Anionic Amphiphile-independent Activation of the Phagocyte NADPH Oxidase in a Cell-free System by p47 and p67 , Both in C Terminally Truncated Forms

1998 • 72 citations

Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47phox

1999 • 60 citations

An SH3 domain‐mediated interaction between the phagocyte NADPH oxidase factors p40^phox and p47^phox

1996 • 50 citations

Mastoparan as a G Protein Activator

2000 • 13 citations