RNASEL Arg462Gln variant is implicated in up to 13% of prostate cancer cases

Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)

1989 • 2,480 citations

pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells.

1978 • 787 citations

Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L

1997 • 552 citations

Germline mutations in the ribonuclease L gene in families showing linkage with HPC1

2002 • 525 citations

CONCEPTUAL PROBLEMS IN THE DEFINITION AND INTERPRETATION OF ATTRIBUTABLE FRACTIONS

1988 • 400 citations

A dominant negative mutant of 2-5A-dependent RNase suppresses antiproliferative and antiviral effects of interferon.

1993 • 273 citations

Development, multiplexing, and application of ARMS tests for common mutations in the CFTR gene.

1992 • 246 citations

Germline Alterations of the RNASEL Gene, a Candidate HPC1 Gene at 1q25, in Patients and Families with Prostate Cancer

2002 • 235 citations

Combined Analysis of Hereditary Prostate Cancer Linkage to 1q24-25: Results from 772 Hereditary Prostate Cancer Families from the International Consortium for Prostate Cancer Genetics

2000 • 166 citations

A Novel Founder Mutation in the RNASEL Gene, 471delAAAG, Is Associated with Prostate Cancer in Ashkenazi Jews

2002 • 130 citations

Linkage Analysis of Chromosome 1q Markers in 136 Prostate Cancer Families

1998 • 123 citations

Analysis of the RNASEL Gene in Familial and Sporadic Prostate Cancer

2002 • 123 citations