Borrelia burgdorferi is clonal: implications for taxonomy and vaccine development.

The neighbor-joining method: a new method for reconstructing phylogenetic trees.

1987 • 59,130 citations

Lyme Disease—a Tick-Borne Spirochetosis?

1982 • 2,831 citations

PHYLOGENIES FROM MOLECULAR SEQUENCES: INFERENCE AND RELIABILITY

1988 • 2,143 citations

The Spirochetal Etiology of Lyme Disease

1983 • 1,590 citations

Delineation of Borrelia burgdorferi Sensu Stricto, Borrelia garinii sp. nov., and Group VS461 Associated with Lyme Borreliosis

1992 • 882 citations

Biology of Borrelia species

1986 • 577 citations

Protection of Mice Against the Lyme Disease Agent by Immunizing with Recombinant OspA

1990 • 480 citations

Recombination in Escherichia coli and the definition of biological species

1991 • 402 citations

Linear Plasmids of the Bacterium Borrelia burgdorferi Have Covalently Closed Ends

1987 • 379 citations

Antigens of Borrelia burgdorferi recognized during Lyme disease. Appearance of a new immunoglobulin M response and expansion of the immunoglobulin G response late in the illness.

1986 • 374 citations

An OspA serotyping system for Borrelia burgdorferi based on reactivity with monoclonal antibodies and OspA sequence analysis

1993 • 344 citations

Molecular analysis of linear plasmid‐encoded major surface proteins, OspA and OspB, of the Lyme disease spirochaete Borrelia burgdorferi

1989 • 317 citations

Antigenic Variability of Borrelia burgdorferi

1988 • 298 citations

The spirochetal etiology of acrodermatitis chronica atrophicans Herxheimer

1984 • 222 citations

Statistical methods of DNA sequence analysis: detection of intragenic recombination or gene conversion.

1985 • 187 citations

Conserved Arrangement of Nested Genes at the Drosophila Gart Locus

1987 • 184 citations

The severe combined immunodeficiency (scid) mouse. A laboratory model for the analysis of Lyme arthritis and carditis.

1989 • 142 citations

Heterogeneity of outer membrane proteins in Borrelia burgdorferi: comparison of osp operons of three isolates of different geographic origins

1992 • 134 citations

Evaluation of genetic divergence among Borrelia burgdorferi isolates by use of OspA, fla, HSP60, and HSP70 gene probes

1992 • 119 citations

Population genetic analysis of Borrelia burgdorferi isolates by multilocus enzyme electrophoresis

1992 • 119 citations

Borrelia burgdorferi strain 25015: characterization of outer surface protein A and vaccination against infection.

1992 • 104 citations

Nucleotide sequence of a gene encoding theBorrelia burgdorferiflagellin

1989 • 96 citations

New Borrelia burgdorferi antigenic variant isolated from Ixodes dammini from upstate New York

1988 • 55 citations

Genetic polymorphism of the gene encoding the outer surface protein A (OspA) of Borrelia burgdorferi

1992 • 55 citations

Cloning and sequencing of the gene encoding the outer surface protein A (OspA) of a EuropeanBorrelia burgdorferi isolate

1989 • 48 citations

The 93-kilodalton protein of Borrelia burgdorferi: an immunodominant protoplasmic cylinder antigen

1992 • 43 citations

Mapping antibody-binding domains of the major outer surface membrane protein (OspA) of Borrelia burgdorferi

1991 • 37 citations

[Identification of Borrelia isolated in the USSR from Ixodes persulcatus Schulze ticks].

1988 • 33 citations

Immunodiagnosis of Lyme Borreliosis

1989 • 19 citations

Analysis and expression of the Borrelia burgdorferi P/Gau fla gene: Identification of heterogeneity with the B31 strain

1992 • 12 citations