Prognostic significance of proliferating cell nuclear antigen expression in colorectal cancer

A genetic model for colorectal tumorigenesis

1990 • 11,800 citations

Effective Surgical Adjuvant Therapy for High-Risk Rectal Carcinoma

1991 • 1,888 citations

Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some, neoplasms

1990 • 1,454 citations

Existence of two populations of cyclin/proliferating cell nuclear antigen during the cell cycle: association with DNA replication sites.

1987 • 945 citations

Autoantibody to a Nuclear Antigen in Proliferating Cells

1978 • 881 citations

Monoclonal antibody analysis of the proliferating cell nuclear antigen (PCNA) structural conservation and the detection of a nucleolar form

1990 • 736 citations

Abnormal pattern of cell proliferation in the entire colonic mucosa of patients with colon adenoma or cancer

1987 • 311 citations

Flow cytometry, cellular DNA content, and prognosis in human malignancy.

1987 • 258 citations

Tritiated thymidine (phi p, phi h) labeling distribution as a marker for hereditary predisposition to colon cancer.

1983 • 191 citations

Prognostic significance of DNA aneuploidy and cell proliferation in rectal adenocarcinomas

1987 • 179 citations

Pattern of epithelial cell proliferation in colorectal mucosa of normal subjects and of patients with adenomatous polyps or cancer of the large bowel.

1988 • 164 citations

DNA ploidy and cell kinetic measurements as predictors of recurrence and survival in stages B2 and C colorectal adenocarcinoma

1991 • 158 citations

Prognostic implications of proliferative activity and DNA aneuploidy in colonic adenocarcinomas.

1987 • 132 citations

Colonic epithelial cell proliferation in responders and nonresponders to supplemental dietary calcium.

1989 • 125 citations

Retrospective analysis of the prognostic significance of DNA content and proliferative activity in large bowel carcinoma.

1987 • 116 citations

Tritiated Thymidine Incorporation Into Epithelial Cells of Normal-Appearing Colorectal Mucosa of Cancer Patients2

1977 • 103 citations

Immunohistochemical analysis of cell kinetic parameters in colonic adenocarcinomas, adenomas, and normal mucosa

1989 • 102 citations

Study of Human Rectal Epithelial Cells <italic>In Vitro</italic>. II. H<sup>3</sup>-Thymidine Incorporation Into Polyps and Adjacent Mucosa<xref ref-type="fn" rid="FN1">2</xref>

1966 • 101 citations

PLOIDY AND PROLIFERATION PATTERNS IN COLO‐RECTAL ADENOCARCINOMAS RELATED TO DUKES‘ CLASSIFICATION AND TO HISTOPATHOLOGICAL DIFFERENTIATION

1983 • 100 citations

S-phase fractions of colorectal carcinomas related to pathologic and clinical features

1981 • 79 citations

Prognostic implications of proliferative activity and DNA aneuploidy in Astler-Coller Dukes stage C colonic adenocarcinomas.

1991 • 52 citations

DNA/RNA Content and Proliferative Fractions of Colorectal Carcinomas: A Five-Year Prospective Study Relating Flow Cytometry to Survival

1991 • 45 citations

A rapid and simple in vitro method for evaluating human colorectal epithelial proliferation.

1990 • 14 citations