Unrearranged immunoglobulin variable region genes have a functional promoter

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.

1977 • 2,408 citations

The use of thin acrylamide gels for DNA sequencing

1978 • 1,449 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.

1980 • 1,285 citations

In vivo sequence requirements of the SV40 early promoter region

1981 • 1,156 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

Promoter Sequences of Eukaryotic Protein-Coding Genes

1980 • 971 citations

Enhanced autoradiographic detection of ³²P and ¹²⁵I using intensifying screens and hypersensitized film

1977 • 947 citations

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

1979 • 859 citations

Spliced early mRNAs of simian virus 40

1978 • 817 citations

Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions.

1976 • 726 citations

Selective and accurate initiation of transcription at the ad2 major late promotor in a soluble system dependent on purified rna polymerase ii and dna

1979 • 678 citations

Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: Identification of an upstream control region

1981 • 646 citations

The nucleotide sequence of the initiation and termination sites for ribosomal rna transcription in x. laevis

1979 • 579 citations

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

1979 • 472 citations

α-globin-gene switching during the development of chicken embryos: Expression and chromosome structure

1981 • 353 citations

Promoters and heterogeneous 5′ termini of the messenger RNAs of adenovirus serotype 2

1981 • 289 citations

The SV40 early region TATA box is required for accurate in vitro initiation of transcription

1981 • 269 citations

Regulation of simian virus 40 early transcription in vitro by a purified tumor antigen.

1980 • 254 citations

Structure and in Vitro Transcription of Human Globin Genes

1980 • 231 citations

The primary structure of the human ε-globin gene

1980 • 195 citations

Transcription of the unrearranged mouse Cκ locus: Sequence of the initiation region and comparison of activity with a rearranged Vκ-Cκ gene

1981 • 190 citations

Differences between germ-line and rearranged immunoglobulin Vκ coding sequences suggest a localized mutation mechanism

1981 • 161 citations

Localization of DNA sequences necessary for transcription of the rabbit β-globin gene in vitro

1981 • 158 citations

Purified DNAs are transcribed after microinjection into Xenopus oocytes.

1977 • 158 citations

Selective DNA conservation and chromatin assembly after injection of SV40 DNA into Xenopus oocytes

1978 • 152 citations

Human immunoglobulin variable region genes—DNA sequences of two Vκ genes and a pseudogene

1980 • 139 citations

Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes.

1980 • 138 citations

Human Vκ immunoglobulin gene number: Implications for the origin of antibody diversity

1981 • 111 citations

Expression of a chicken chromosomal ovalbumin gene injected into frog oocyte nuclei

1980 • 93 citations

Promotion of specific in vitro transcription by excised “TATA” box sequences inserted in a foreign nucleotide environment

1981 • 90 citations

Quantitative analysis of specific labelled RNA's using DNA covalently linked to diazobenzyloxy-methyl-paper

1979 • 87 citations

Transcriptional regulation of immunoglobulin V genes

1981 • 81 citations

Cloning of nematode tRNA genes and their expression in the frog oocyte.

1978 • 76 citations

Specific 5′ flanking sequences are required for faithful initiation of in vitro transcription of the ovalbumin gene

1981 • 74 citations

[7] Synthetic adaptors for cloning DNA

1979 • 69 citations

Evidence for noncontiguous variable and constant region genes in both germ line and myeloma DNA

1978 • 63 citations

Transcriptional fidelity of histone genes injected into Xenopus oocyte nuclei

1980 • 46 citations

Transcription units of chicken ovalbumin gene observed after injection of cloned complete genes into Xenopus oocyte nuclei.

1980 • 23 citations