The polymerization mechanism of the bacterial cell division protein FtsZ

Dynamic instability of microtubule growth

1984 • 3,187 citations

MICROTUBULE POLYMERIZATION DYNAMICS

1997 • 2,442 citations

Structure of the αβ tubulin dimer by electron crystallography

1998 • 2,006 citations

FtsZ ring structure associated with division in Escherichia coli

1991 • 1,417 citations

High-Resolution Model of the Microtubule

1999 • 1,138 citations

Crystal structure of the bacterial cell-division protein FtsZ

1998 • 883 citations

Structural Insights into Microtubule Function

2000 • 750 citations

Tubulin and FtsZ form a distinct family of GTPases

1998 • 571 citations

The essential bacterial cell-division protein FtsZ is a GTPase

1992 • 544 citations

Bacterial cell division protein FtsZ assembles into protofilament sheets and minirings, structural homologs of tubulin polymers.

1996 • 452 citations

Escherichia coli cell-division gene ftsZ encodes a novel GTP-binding protein

1992 • 424 citations

The Polyelectrolyte Nature of F-actin and the Mechanism of Actin Bundle Formation

1996 • 398 citations

Guanine nucleotide-dependent assembly of FtsZ into filaments

1994 • 381 citations

Dynamic assembly of FtsZ regulated by GTP hydrolysis

1998 • 362 citations

Chloroplast Division in Higher Plants Requires Members of Two Functionally Divergent Gene Families with Homology to Bacterial ftsZ

1998 • 330 citations

Escherichia coli cell division protein FtsZ is a guanine nucleotide binding protein.

1993 • 316 citations

Straight and Curved Conformations of FtsZ Are Regulated by GTP Hydrolysis

2000 • 291 citations

Themes and variations in prokaryotic cell division

2000 • 288 citations

Analysis of FtsZ Assembly by Light Scattering and Determination of the Role of Divalent Metal Cations

1999 • 263 citations

GTP-dependent polymerization of Escherichia coli FtsZ protein to form tubules.

1994 • 258 citations

Ca2+-mediated GTP-dependent dynamic assembly of bacterial cell division protein FtsZ into asters and polymer networks invitro

1997 • 243 citations

Analysis of the interaction of FtsZ with itself, GTP, and FtsA

1997 • 220 citations

Tubulin-like protofilaments in Ca2+-induced FtsZ sheets

1999 • 213 citations

ZipA-Induced Bundling of FtsZ Polymers Mediated by an Interaction between C-Terminal Domains

2000 • 203 citations

Polymerization of FtsZ, a Bacterial Homolog of Tubulin

2001 • 203 citations

FtsZ Dynamics during the Division Cycle of Live Escherichia coli Cells

1998 • 200 citations

FtsZ‐spirals and ‐arcs determine the shape of the invaginating septa in some mutants of Escherichia coli

1996 • 194 citations

Timing of FtsZ Assembly in Escherichia coli

1999 • 193 citations

ZipA is a MAP–Tau homolog and is essential for structural integrity of the cytokinetic FtsZ ring during bacterial cell division

1999 • 187 citations

Magnesium-induced Linear Self-association of the FtsZ Bacterial Cell Division Protein Monomer

2000 • 184 citations

Direct observation of the enhancement of noncooperative protein self-assembly by macromolecular crowding: Indefinite linear self-association of bacterial cell division protein FtsZ

2001 • 183 citations

Bacterial SOS Checkpoint Protein SulA Inhibits Polymerization of Purified FtsZ Cell Division Protein

1998 • 180 citations

FtsZ fromEscherichia coli,Azotobacter vinelandii, andThermotoga maritima—quantitation, GTP hydrolysis, and assembly

1998 • 178 citations

Guanosinetriphosphatase activity of tubulin associated with microtubule assembly.

1977 • 174 citations

Mitochondrial FtsZ in a Chromophyte Alga

2000 • 172 citations

The FtsZ protein of Bacillus subtilis is localized at the division site and has GTPase activity that is dependent upon FtsZ concentration

1993 • 156 citations

FtsZ ring: the eubacterial division apparatus conserved in archaebacteria

1996 • 136 citations

Slow Polymerization of Mycobacterium tuberculosis FtsZ

2000 • 126 citations

Temperature shift experiments with an ftsZ84(Ts) strain reveal rapid dynamics of FtsZ localization and indicate that the Z ring is required throughout septation and cannot reoccupy division sites once constriction has initiated

1997 • 122 citations

Analysis of ftsZ mutations that confer resistance to the cell division inhibitor SulA (SfiA)

1990 • 118 citations

Mutations in ftsZ that confer resistance to SulA affect the interaction of FtsZ with GTP

1994 • 110 citations

Site-specific mutations of FtsZ--effects on GTPase and in vitro assembly.

2001 • 96 citations

Cell division inhibitors SulA and MinC/MinD block septum formation at different steps in the assembly of the Escherichia coli division machinery

2000 • 93 citations

Escherichia coli FtsZ polymers contain mostly GTP and have a high nucleotide turnover

2001 • 88 citations

Isolation and characterization of ftsZ alleles that affect septal morphology

1992 • 87 citations

Self-Activation of Guanosine Triphosphatase Activity by Oligomerization of the Bacterial Cell Division Protein FtsZ

1999 • 77 citations

Chromosome replication, nucleoid segregation and cell division in Archaea

2000 • 75 citations

A set of ftsZ mutants blocked at different stages of cell division in Caulobacter

2001 • 62 citations

Activation of Cell Division Protein FtsZ

2001 • 58 citations

Non‐hydrolysable GTP‐γ‐S stabilizes the FtsZ polymer in a GDP‐bound state

2000 • 57 citations

A point mutation converts Escherichia coli FtsZ septation GTPase to an ATPase.

1994 • 53 citations

Helical Tubes of FtsZ from Methanococcus jannaschii

2000 • 41 citations

Substitution of a conserved aspartate allows cation‐induced polymerization of FtsZ

2001 • 31 citations