Secondary structure of the self-cleaving RNA of hepatitis delta virus: applications to catalytic RNA design

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

[1] Production of single-stranded plasmid DNA

1987 • 2,642 citations

DNA sequence analysis with a modified bacteriophage T7 DNA polymerase.

1987 • 2,266 citations

Improved free-energy parameters for predictions of RNA duplex stability.

1986 • 1,472 citations

Probing the structure of RNAs in solution

1987 • 721 citations

Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites

1987 • 660 citations

Self-cleavage of plus and minus RNA transcripts of avocado sunblotch viroid

1986 • 583 citations

Antigenomic RNA of human hepatitis delta virus can undergo self-cleavage

1988 • 385 citations

CUUCGG hairpins: extraordinarily stable RNA secondary structures associated with various biochemical processes.

1988 • 357 citations

A pseudoknot-like structure required for efficient self-cleavage of hepatitis delta virus RNA

1991 • 339 citations

Characterization of self-cleaving RNA sequences on the genome and antigenome of human hepatitis delta virus

1988 • 321 citations

Human hepatitis delta virus RNA subfragments contain an autocleavage activity.

1989 • 284 citations

Catalysis of RNA cleavage by the Tetrahymena thermophila ribozyme. 1. Kinetic description of the reaction of an RNA substrate complementary to the active site

1990 • 280 citations

‘Hairpin’ catalytic RNA model: evidence for helices and sequence requirement for substrate RNA

1990 • 232 citations

On the recognition of helical RNA by cobra venom V1 nuclease.

1986 • 160 citations

The self-cleaving domain from the genomic RNA of hepatitis delta virus: sequence requirements and the effects of denaturant

1990 • 126 citations

Cleavage of oligoribonucleotides by a ribozyme derived from the hepatitis .delta. virus RNA sequence

1992 • 120 citations

Efficient trans cleavage and a common structural motif for the ribozymes of the human hepatitis delta agent.

1991 • 104 citations

Self-cleavage of hepatitis delta virus genomic strand RNA is enhanced under partially denaturing conditions

1990 • 86 citations

Sequence and structure of the catalytic RNA of hepatitis delta virus genomic RNA

1992 • 76 citations

Evidence that genomic and antigenomic RNA self-cleaving elements from hepatitis delta virus have similar secondary structures

1991 • 73 citations

Comparison of the kinetics of ribo-, deoxyribo- and hybrid oligonucleotide double-strand formation by temperature-jump kinetics

1982 • 60 citations

Antigenomic Hepatitis delta virus ribozymes self-cleave in 18 M formamide

1991 • 46 citations

Specific association between an endoribonucleolytic sequence from a satellite RNA and a substrate analogue containing a 2'-5' phosphodiester.

1990 • 41 citations

Non-ribozyme sequences enhance self-cleavage of ribozymes derived from Hepatitis delta virus

1991 • 33 citations

Self-cleavage of a 71 nucleotide-long ribozyme derived from hepatitis delta virus genomic RNA

1991 • 29 citations

Deletion of internal sequence on the HDV-ribozyme: elucidation of functionally important single-stranded loop regions

1992 • 25 citations