Pharmacokinetics and bioavailability of midazolam after intravenous, subcutaneous, intraperitoneal and oral administration under a chronic food-limited regimen: relating DRL performance to pharmacokinetics

Arzneimittelforschung

2005 • 8,820 citations

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

1989 • 528 citations

Species similarities and differences in pharmacokinetics.

1995 • 364 citations

Pharmacokinetics and bioavailability of midazolam in man.

1983 • 286 citations

Pharmacology of midazolam.

1981 • 150 citations

The erythromycin breath test predicts the clearance of midazolam*

1995 • 132 citations

Excretion and metabolism of 14C-midazolam in humans following oral dosing.

1981 • 117 citations

Influence of nutrients and other dietary materials on cytochrome P-450 enzymes

1995 • 113 citations

Relationship between plasma concentration and effect of midazolam after oral and intravenous administration.

1983 • 112 citations

The effects of alprazolam on corticotropin-releasing factor neurons in the rat brain: acute time course, chronic treatment and abrupt withdrawal.

1991 • 90 citations

Pharmacokinetic‐pharmacodynamic modelling of the EEG effects of midazolam in individual rats: influence of rate and route of administration

1991 • 83 citations

Heterogeneity of cytochrome P450IIIA expression in rat gut epithelia

1992 • 76 citations

Dose dependent pharmacokinetics of midazolam

1985 • 67 citations

Dose-dependent kinetics of caffeine in rats

1978 • 53 citations

Triazolam Pharmacokinetics After Intravenous, Oral, and Sublingual Administration

1995 • 52 citations

BOOMER, a simulation and modeling program for pharmacokinetic and pharmacodynamic data analysis

1989 • 47 citations

Tissue distribution of 14C-diazepam and its metabolites in rats.

1982 • 39 citations

A pharmacokinetic/pharmacodynamic/receptor binding model to predict the onset and duration of pharmacological activity of the benzodiazepines

1983 • 35 citations

Simultaneous determination of flurazepam and five metabolites in serum by high-performance liquid chromatography and its application to pharmacokinetic studies in rats

1987 • 32 citations

Modulation of drug metabolism by food restriction in male rats

1982 • 30 citations

[Relation between the clinical effect and the pharmacokinetics of midazolam following i.m. and i.v. administration/2nd comm.: Pharmacokinetical aspects (author's transl)].

1981 • 26 citations

Onset and duration of action of benzodiazepines as determined by inhibition of (3H)‐flunitrazepam binding

1987 • 20 citations

Alprazolam, caffeine and their interaction: relating DRL performance to pharmacokinetics

1996 • 19 citations

Midazolam and discriminative motor control: chronic administration, withdrawal and modulation by the antagonist Ro 15-1788.

1988 • 18 citations

Oral and IP caffeine pharmacokinetics under a chronic food-limitation condition

1995 • 18 citations

Sustained synergism by chronic caffeine of the motor control deficit produced by midazolam

1991 • 13 citations

Motor performance decrement by midazolam: Antagonism by Ro 15-1788 and CGS 8216

1990 • 11 citations