Inhibition of viral reverse transcriptase by 2′,5′-oligoadenylates

Biochemistry of Interferons and Their Actions

1982 • 868 citations

Interferon-induced enzymatic activities and their role in the antiviral state

1979 • 392 citations

Chemotherapeutic approaches to the treatment of the acquired immune deficiency syndrome (AIDS)

1986 • 251 citations

Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells

1980 • 242 citations

The reverse transcriptase

1977 • 194 citations

Inhibition of protein synthesis by 2′–5′ linked adenine oligonucleotides in intact cells

1978 • 182 citations

Synthesis of 2'5'-oligo(A) in extracts of interferon-treated HeLa cells.

1979 • 174 citations

Anticellular and antiviral effects of pppA(2′p5′A)n

1980 • 164 citations

Variation of DNA polymerases - α , - β . and - γ during perinatal tissue growth and differentiation

1977 • 106 citations

Eukaryotic DNA polymerase alpha. Structural analysis of the enzyme from regenerating rat liver.

1980 • 88 citations

Molecular Biology: Reverse Transcriptase, the DNA Polymerase of Oncogenic RNA Viruses

1971 • 83 citations

2-5A accumulates to high levels in interferon-treated, vaccinia virus-infected cells in the absence of any inhibition of virus replication

1984 • 82 citations

2‘,5‘-Oligoadenylate synthetase activity in lymphocytes from normal mouse.

1979 • 71 citations

Reverse transcriptase from avian myeloblastosis virus

1979 • 68 citations

Presence of 2',5'-oligo(A) and of enzymes that synthesize, bind, and degrade 2',5'-oligo(A) in HeLa cell nuclei.

1982 • 64 citations

Simian virus 40-infected, interferon-treated cells contain 2‘,5‘-oligoadenylates which do not activate cleavage of RNA.

1984 • 56 citations

The 2–5A (pppA2′ p5′ A2′ p5′ A) system in interferon-treated and control cells

1980 • 55 citations

Cleavage of nascent reovirus mRNA by localized activation of the 2'-5'-oligoadenylate-dependent endoribonuclease

1984 • 43 citations

Degradation of rRNA in interferon-treated vaccinia virus-infected cells.

1984 • 37 citations

Pyridoxal 5′ phosphate: A selective inhibitor of oncornaviral DNA polymerases

1976 • 34 citations

2'-5'-Linked oligo(adenylic acid) and its analogs. A new class of inhibitors of mRNA methylation.

1982 • 26 citations

Observations on the suramin-mediated inhibition of cellular and viral DNA polymerases

1985 • 24 citations

Analysis of 2′,5′-oligoadenylates in cells and tissues

1984 • 17 citations

Regulation of 2–5 A synthetase activity and antiviral state in interferon treated chick cells

1982 • 17 citations

Differential effects of captan on DNA polymerase and ribonuclease H activities of avian myeloblastosis virus reverse transcriptase

1986 • 10 citations

Inhibition of DNA polymerase α activity by proteins from rat liver

1985 • 9 citations

Cell-free synthesis of tumor-type poly(A) polymerase

1986 • 8 citations

Phenobarbital enhances 2′, 5′-oligoadenylate synthesis in rat liver nuclei

1984 • 5 citations