The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

2010 • 864 citations

BRCA2 Function in DNA Binding and Recombination from a BRCA2-DSS1-ssDNA Structure

2002 • 679 citations

PALB2 is an integral component of the BRCA complex required for homologous recombination repair

2009 • 567 citations

Purification and characterization of the human Rad51 protein, an analogue of E. coli RecA.

1994 • 452 citations

CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

2005 • 449 citations

Targeted Inactivation of Mouse RAD52Reduces Homologous Recombination but Not Resistance to Ionizing Radiation

1998 • 317 citations

The BRCA2 homologue Brh2 nucleates RAD51 filament formation at a dsDNA–ssDNA junction

2005 • 315 citations

Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2

2003 • 260 citations

The BRC Repeats of BRCA2 Modulate the DNA-Binding Selectivity of RAD51

2009 • 246 citations

Rad52 Protein Associates with Replication Protein A (RPA)-Single-stranded DNA to Accelerate Rad51-mediated Displacement of RPA and Presynaptic Complex Formation

2002 • 238 citations

Functional Interactions among Yeast Rad51 Recombinase, Rad52 Mediator, and Replication Protein A in DNA Strand Exchange

2000 • 175 citations

Assembly of RecA-like recombinases: Distinct roles for mediator proteins in mitosis and meiosis

2001 • 160 citations

Interactions between human BRCA2 protein and the meiosis-specific recombinase DMC1

2007 • 114 citations

The Carboxyl Terminus of Brca2 Links the Disassembly of Rad51 Complexes to Mitotic Entry

2009 • 97 citations

A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange

2006 • 80 citations

The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange

2009 • 69 citations

CeBRC-2 Stimulates D-loop Formation by RAD-51 and Promotes DNA Single-strand Annealing

2006 • 67 citations

Dss1 Interaction with Brh2 as a Regulatory Mechanism for Recombinational Repair

2007 • 41 citations

Cancer-Associated Mutations in BRC Domains of BRCA2 Affect Homologous Recombination Induced by Rad51

2009 • 33 citations

Evidence that the tumor-suppressor protein BRCA2 does not regulate cytokinesis in human cells

2010 • 29 citations

Inactivation of RAD52 aggravates RAD54 defects in mice but not in Schizosaccharomyces pombe

2005 • 14 citations