A common mechanism of hapten binding to immunoglobulins and their heterologous chain recombinants

On the nature of allosteric transitions: A plausible model

1965 • 8,699 citations

On the analysis of fluorescence decay kinetics by the method of least-squares

1974 • 803 citations

Structure of a λ-type Bence-Jones protein at 3.5-Å resolution

1973 • 356 citations

A temperature‐jump apparatus for fluorescence measurements

1974 • 171 citations

Kinetic Analysis by Chemical Relaxation Methods

1968 • 109 citations

Antigen-induced conformational changes in antibodies and their Fab fragments studied by circular polarization of fluorescence.

1975 • 106 citations

Calculation of the Spectrum of Chemical Relaxation Times for a General Reaction Mechanism

1963 • 100 citations

Kinetic evidence for hapten-induced conformational transition in immunoglobin MOPC 460.

1976 • 95 citations

Structural basis for the specificity of antibody–antigen reactions and structural mechanisms for the diversification of antigen-binding specificities

1977 • 94 citations

Three-dimensional structure, function and genetic control of immunoglobulins

1975 • 80 citations

Structural evidence for independent joining region gene in immunoglobulin heavy chains from anti-galactan myeloma proteins and its potential role in generating diversity in complementarity-determining regions

1979 • 71 citations

Spectral changes on binding of oligosaccharides to murine immunoglobulin A myeloma proteins

1973 • 65 citations

Equilibrium and kinetic aspects of the interaction of isolated variable and constant domains of light chain with the Fd' fragment of immunoglobulin G

1979 • 61 citations

Conformational changes induced in a homogeneous antitype III pneumococcal antibody by oligosaccharides of increasing size

1975 • 60 citations

Binding of 4-methylumbelliferyl α-D-mannopyranoside to dimeric concanavalin A: fluorescence temperature-jump relaxation study

1977 • 51 citations

Subunit interactions in mouse myeloma proteins with anti-galactan activity.

1976 • 38 citations

Changes in Intrinsic Circular Dichroism of Several Homogeneous Anti-Type III Pneumococcal Antibodies on Binding of a Small Hapten

1972 • 38 citations

Studies on the three-dimensional structure of immunoglobulins

1978 • 38 citations

Hapten-linked conformational equilibria in immunolglobulins XRPC-24 and J-539 observed by chemical relaxation

1978 • 24 citations

Binding of 4-Methylumbelliferyl alpha-d-Mannopyranoside to Tetrameric Concanavalin A. Fluorescence Temperature-Jump Relaxation Study

1977 • 22 citations

Kinetics of binding of oligosaccharides to a homogeneous pneumococcal antibody: dependence on antigen chain length suggests a labile intermediate complex

1977 • 20 citations

Effect of interchain disulfide bond on hapten binding properties of light chain dimer of protein 315.

1979 • 18 citations

Evidence for mobility of immunoglobulin domains obtained by spin-label method

1976 • 16 citations

Hapten-induced structural changes in rabbit immunoglobulin G with specifically mercuriated inter-heavy-chain disulfide

1979 • 15 citations

The formation of active hybrid immunoglobulins from the heavy and light chains of beta(1, 6) D-galactan binding murine myeloma IgA's S10 and J539.

1977 • 14 citations

Hapten-induced allosteric transition in the light chain dimer of an immunoglobulin

1977 • 14 citations

Conformational transitions of antibodies induced by hapten binding

1977 • 9 citations