Rat liver chitobiase: Purification, properties, and role in the lysosomal degradation of Asn-linked glycoproteins

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

The Metabolic Basis of Inherited Disease.

1983 • 2,885 citations

A MODIFIED COLORIMETRIC METHOD FOR THE ESTIMATION OF N-ACETYLAMINO SUGARS

1955 • 2,574 citations

A SUBMICRODETERMINATION OF GLUCOSE

1949 • 1,578 citations

Identification, developmental regulation, and response to heat shock of two antigenically related forms of a major nuclear envelope protein in Drosophila embryos: application of an improved method for affinity purification of antibodies using polypeptides immobilized on nitrocellulose blots

1984 • 668 citations

Lysosomes : their role in protein breakdown

1987 • 435 citations

The structural basis of the different affinities of two types of acidic N‐glycosidic glycopeptides for concanavalin a—sepharose

1976 • 277 citations

Digestive Activity of Lysosomes

1968 • 219 citations

Lysosomal alpha-D-mannosidase of rat liver. Purification and comparison with the golgi and cytosolic alpha-D-mannosidases

1978 • 135 citations

Endoglycosidases acting on carbohydrate moieties of glycoproteins: Demonstration in mammalian tissue

1974 • 94 citations

Cytosolic location of an endo-N-acetyl-β-D-glucosaminidase activity in rat liver and kidney

1979 • 91 citations

Studies on Enzymes Acting on Glycopeptides*

1968 • 83 citations

The similar effects of swainsonine and locoweed on tissue glycosidases and oligosaccharides of the pig indicate that the alkaloid is the principal toxin responsible for the induction of locoism

1984 • 83 citations

The purification and properties of a β-aspartyl N-acetylglucosylamine amidohydrolase from hen oviduct

1969 • 80 citations

Caprine oligosaccharide storage disease. Accumulation of beta-mannosyl (1 goes to 4) beta-N-acetylglucosaminyl (1 goes to 4) beta-N-acetylglucosamine in brain.

1981 • 79 citations

The purification and characterization of rat liver lysosomal alpha-L-fucosidase.

1977 • 65 citations

A di-N-acetylchitobiase activity is involved in the lysosomal catabolism of asparagine-linked glycoproteins in rat liver.

1986 • 63 citations

Novel carbohydrate structures of cathepsin B from porcine spleen.

1984 • 58 citations

Production of hybrid glycoproteins and accumulation of oligosaccharides in the brain of sheep and pigs administered swainsonine or locoweed

1988 • 57 citations

Demonstration and cytosolic location of an endo-N-acetyl-β-D-glucosaminidase activity towards an asialo-N-acetyl-lactosaminic-type substrate in rat liver

1980 • 56 citations

Substrate specificity of mammalian endo-β-N-acetylglucosaminidase: Study with the enzyme of rat liver

1982 • 53 citations

GENETIC DEFECTS IN GLYCOPROTEIN METABOLISM

1983 • 52 citations

Isolation and structure of the core oligosaccharide sequences of IgM

1975 • 51 citations

The catabolism of mammalian glycoproteins. Comparison of the storage products in bovine, feline and human mannosidosis

1983 • 47 citations

Swainsonine-induced oligosaccharide excretion in sheep. Time-dependent changes in the oligosaccharide profile

1984 • 41 citations

Catabolism of glycoprotein glycans. Characterization of a lysosomal endo-N-acetyl-beta-d-glucosaminidase specific for glycans with a terminal chitobiose residue

1986 • 41 citations

Structure and mass analysis of 14S dynein obtained from Tetrahymena cilia.

1988 • 40 citations

Swainsonine affects the processing of glycoproteins in vivo

1983 • 39 citations

Structure analysis of the major oligosaccharides accumulating in canine GM1 gangliosidosis liver.

1982 • 38 citations

Human N‐acetyl‐β‐hexosaminidases: Hydrolysis of N,N′diacetylchitobiose by a low molecular weight enzyme

1974 • 38 citations

GM1 gangliosidosis (type 1) in a cat

1986 • 27 citations

Absence of endo-β-N-acetylglucosaminidase activity in the kidneys of sheep, cattle and pig

1987 • 26 citations

Catabolism of N-glycosylprotein glycans: evidence for a degradation pathway of sialyglyco-asparagines resulting from the combined action of the lysosomal aspartylglucosaminidase and endo-N-acetyl-beta-d-glucosaminidase. A 400-MHz 1H-NMR study

1987 • 25 citations

Structural analysis of the major urinary oligosaccharides in feline α-mannosidosis

1986 • 24 citations

Use of active site-directed inhibitors to study in situ degradation of glycoproteins by the perfused rat liver.

1985 • 23 citations

A convenient synthetic route to the disaccharide repeating-unit of peptidoglycan

1987 • 19 citations

Degradation of [6-3H]- and [1-14C]glucosamine-labeled asialo-alpha 1-acid glycoprotein by the perfused rat liver.

1983 • 18 citations

Use of radioactive glucosamine in the perfused rat liver to prepare α1-acid glycoprotein (orosomucoid) with 3H- or 14C-labelled sialic acid and N-acetylglucosamine residues

1982 • 9 citations

Uptake and degradation of 125I-labeled rat asialoorosomucoid by the perfused rat liver

1984 • 5 citations