NMDA depolarizations and long-term potentiation are reduced in the aged rat neocortex

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1986 • 3,586 citations

Psychopharmacology: The third generation of progress

1988 • 3,403 citations

Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat.

1979 • 1,970 citations

Long-term potentiation and NMDA receptors in rat visual cortex

1987 • 953 citations

Long-term potentiation in the hippocampus involves activation of N-methyl-D-aspartate receptors

1984 • 905 citations

Specific long-lasting potentiation of synaptic transmission in hippocampal slices

1977 • 493 citations

Excitatory Amino Acid Neurotransmission: NMDA Receptors and Hebb-Type Synaptic Plasticity

1988 • 484 citations

Long-Term Synaptic Potentiation

1988 • 417 citations

Glutamate dysfunction in Alzheimer's disease: an hypothesis

1987 • 335 citations

Physiological compensation for loss of afferent synapses in rat hippocampal granule cells during senescence.

1980 • 285 citations

A magnesium‐sensitive post‐synaptic potential in rat cerebral cortex resembles neuronal responses to N‐methylaspartate.

1986 • 249 citations

Potential Animal Models for Senile Dementia of Alzheimer's Type, with Emphasis on AF64A-Induced Cholinotoxicity

1986 • 148 citations

Presynaptic and postsynaptic glutamatergic function in Alzheimer's disease

1988 • 96 citations

The effects of serotonin on N-methyl-d-aspartate and synaptically evoked depolarizations in rat neocortical neurons

1988 • 87 citations

Sustained enhancement of evoked potentials following brief, high-frequency stimulation of the cerebral cortex in vitro

1982 • 81 citations

Conformational changes in muscarinic receptors may produce diminished cholinergic neurotransmission and memory deficits in aged rats

1985 • 81 citations

Linear relation between the magnitude of long-term potentiation in the dentate gyrus and associative learning in the rat. A demonstration using commissural inhibition and local infusion of an N-methyl-d-aspartate receptor antagonist

1989 • 79 citations

Long-term potentiation in frontal cortex: Role of NMDA-modulated polysynaptic excitatory pathways

1989 • 48 citations

Altered modulatory actions of serotonin on dentate granule cells of aged rats

1987 • 45 citations

The postnatal development of post-activation potentiation in the rat neocortex

1983 • 44 citations

Acetylcholine, aging and anatomy: differential effects in the hippocampus

1986 • 42 citations

Age-related reduction in responses of rat hippocampal neurons to locally applied monoamines

1988 • 41 citations

Membrane properties and aging: in vivo and in vitro effects of ethanol on synaptosomal gamma-aminobutyric acid (GABA) release.

1984 • 35 citations

[Prolonged potentiation of responses of the neocortex of the intact brain and in vitro cortical slices].

1984 • 6 citations