Mycobacterial heat shock protein 70 induces interleukin-10 production: immunomodulation of synovial cell cytokine profile and dendritic cell maturation

Interleukin-10 and the Interleukin-10 Receptor

2001 • 6,422 citations

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

Characterization of Dendritic Cells that Induce Tolerance and T Regulatory 1 Cell Differentiation In Vivo

2003 • 811 citations

Removal of endotoxin from protein solutions by phase separation using triton X-114

1990 • 584 citations

Toll receptors, CD14, and macrophage activation and deactivation by LPS

2002 • 557 citations

Development of Th1-Inducing Capacity in Myeloid Dendritic Cells Requires Environmental Instruction

2000 • 514 citations

Microbial Compounds Selectively Induce Th1 Cell-Promoting or Th2 Cell-Promoting Dendritic Cells In Vitro with Diverse Th Cell-Polarizing Signals

2002 • 507 citations

Endotoxin Contamination in Recombinant Human Heat Shock Protein 70 (Hsp70) Preparation Is Responsible for the Induction of Tumor Necrosis Factor α Release by Murine Macrophages

2002 • 399 citations

Dendritic Cells as Sensors of Infection

2001 • 324 citations

Stimulation of Th1-Polarizing Cytokines, C-C Chemokines, Maturation of Dendritic Cells, and Adjuvant Function by the Peptide Binding Fragment of Heat Shock Protein 70

2002 • 267 citations

Endotoxin-free heat-shock protein 70 fails to induce APC activation

2002 • 244 citations

A Conserved Mycobacterial Heat Shock Protein (hsp) 70 Sequence Prevents Adjuvant Arthritis upon Nasal Administration and Induces IL-10-Producing T Cells That Cross-React with the Mammalian Self-hsp70 Homologue

2000 • 227 citations

Do heat shock proteins control the balance of T-cell regulation in inlammatory diseases?

1998 • 171 citations

In Vivo Cytotoxic T Lymphocyte Elicitation by Mycobacterial Heat Shock Protein 70 Fusion Proteins Maps to a Discrete Domain and Is Cd4+ T Cell Independent

2000 • 125 citations

The ability of murine dendritic cell subsets to direct T helper cell differentiation is dependent on microbial signals

2002 • 120 citations

The tetracycline derivative minocycline differentially affects cytokine production by monocytes and T lymphocytes

1996 • 117 citations

Mycobacterial heat‐shock proteins as carrier molecules. II: The use of the 70‐kDa mycobacterial heat‐shock protein as carrier for conjugated vaccinescan circumvent the need for adjuvants and Bacillus Calmette Guérin priming)

1992 • 114 citations

A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis

1996 • 103 citations

Randomized, double-blind trial of anti-interferon-?antibodies in rheumatoid arthritis

2001 • 94 citations

Activation of T Cells Recognizing an Epitope of Heat-Shock Protein 70 Can Protect Against Rat Adjuvant Arthritis

1999 • 89 citations

Induction of IL-10 and Inhibition of Experimental Arthritis Are Specific Features of Microbial Heat Shock Proteins That Are Absent for Other Evolutionarily Conserved Immunodominant Proteins

2001 • 81 citations

Biochemical and antigenic characterization of the Mycobacterium tuberculosis 71 kD antigen, a member of the 70 kD heat‐shock protein family

1989 • 80 citations

ATP and ADP hydrolysis in brain membranes of zebrafish (Danio rerio)

2003 • 77 citations

Effects of mercury on myosin ATPase in the ventricular myocardium of the rat

2003 • 41 citations

The regulatory role of heat shock protein 70-reactive CD4+ T cells during rat listeriosis.

1998 • 39 citations

Hereditary predisposition to low interleukin‐10 production in children with extended oligoarticular juvenile idiopathic arthritis

2001 • 35 citations

Changes in nucleotide hydrolysis in rat blood serum induced by pentylenetetrazol-kindling

2003 • 29 citations

Interleukin 10 (IL-10), not IL-4 or interferon-gamma production, correlates with progression of joint destruction in rheumatoid arthritis.

2001 • 28 citations

Overexpression of monocyte-derived cytokines in active psoriasis: a relation to coexistent arthropathy

1999 • 24 citations

Characteristics of the strong antibody response to mycobacterial Hsp70: a primary, T cell-dependent IgG response with no evidence of natural priming or gamma delta T cell involvement.

1998 • 23 citations

Mycobacterium paratuberculosis heat shock protein 70 as a tool in control of paratuberculosis

2002 • 19 citations

Characteristics of the Strong Antibody Response to Mycobacterial Hsp70: A Primary, T Cell-Dependent IgG Response with no Evidence of Natural Priming or γδ T Cell Involvement

1998 • 19 citations

Different sensitivity of Ca2+-ATPase and cholinesterase to pure and commercial pesticides in nervous ganglia of Phyllocaulis soleiformis (Mollusca)

2003 • 16 citations

Acute caffeine treatment increases extracellular nucleotide hydrolysis from rat striatal and hippocampal synaptosomes.

2003 • 13 citations

In vitro effects of thyroid hormones on ectonucleotidase activities in synaptosomes from hippocampus of rats.

2002 • 12 citations

ATP diphosphohydrolase in human platelets from patients with coronary arteries heart disease

2003 • 11 citations

Immunity to Heat Shock Proteins and Arthritic Disorders

1999 • 8 citations

Effects of phenylalanine and phenylpyruvate on ATP-ADP hydrolysis by rat blood serum

2003 • 8 citations

Immunity to heat shock proteins and arthritic disorders

1999 • 4 citations