Epileptic activity outlasts disinhibition after intrahippocampal tetanus toxin in the rat.

A permanent change in brain function resulting from daily electrical stimulation

1969 • 3,056 citations

Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

1992 • 1,792 citations

Decreased Hippocampal Inhibition and a Selective Loss of Interneurons in Experimental Epilepsy

1987 • 1,077 citations

Paired‐pulse depression of monosynaptic GABA‐mediated inhibitory postsynaptic responses in rat hippocampus.

1990 • 709 citations

Permanently altered hippocampal structure, excitability, and inhibition after experimental status epilepticus in the rat: The “dormant basket cell” hypothesis and its possible relevance to temporal lobe epilepsy

1991 • 706 citations

Mossy fiber synaptic reorganization induced by kindling: time course of development, progression, and permanence

1991 • 539 citations

Dormancy of Inhibitory Interneurons in a Model of Temporal Lobe Epilepsy

1993 • 231 citations

Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport

1979 • 229 citations

How does tetanus toxin act?

1981 • 189 citations

Intracellularly injected tetanus toxin inhibits exocytosis in bovine adrenal chromaffin cells

1986 • 183 citations

The effects of tetanus toxin on neuromuscular transmission and on the morphology of motor end‐plates in slow and fast skeletal muscle of the mouse

1973 • 151 citations

Epileptiform syndrome in rats produced by injecting tetanus toxin into the hippocampus.

1977 • 142 citations

Role of excitatory amino acid receptors in synaptic transmission in area CA1 of rat hippocampus

1989 • 113 citations

Long-term loss of paired pulse inhibition in the kainic acid-lesioned hippocampus of the rat

1989 • 107 citations

Effects of Tetanus Toxin on Catecholamine Release from Intact and Digitonin‐Permeabilized Chromaffin Cells

1988 • 83 citations

Long‐term changes in hippocampal physiology and learning ability of rats after intrahippocampal tetanus toxin.

1985 • 76 citations

Tetanus toxin: convulsant action on mouse spinal cord neurons in culture

1983 • 70 citations

A long-lasting decrease in the inhibitory effect of GABA on glutamate responses of hippocampal pyramidal neurons induced by kindling epileptogenesis

1991 • 67 citations

The Molecular Basis of Kindling

1993 • 64 citations

Tetanus Toxin in Dissociated Spinal Cord Cultures: Long‐Term Characterization of Form and Action

1986 • 61 citations

A selective decrease in the number of GABAergic somata occurs in pre-seizing monkeys with alumina gel granuloma

1989 • 59 citations

Retrograde transneuronal transport properties of fragment C of tetanus toxin

1990 • 56 citations

A study of the action of tetanus toxin at rat soleus neuromuscular junctions.

1984 • 53 citations

Chronic Epileptic Foci in Neocortex: In Vivo and In Vitro Effects of Tetanus Toxin

1991 • 52 citations

Injection of tetanus toxin into the neocortex elicits persistent epileptiform activity but only transient impairment of GABA release

1993 • 52 citations

PHYSIOLOGICAL AND BEHAVIOURAL CONSEQUENCES OF SEIZURES INDUCED IN THE RAT BY INTRAHIPPOCAMPAL TETANUS TOXIN

1987 • 49 citations

Synaptic inhibition in primary and secondary chronic epileptic foci induced by intrahippocampal tetanus toxin in the rat.

1993 • 49 citations

Sustained and selective block of IPSPs in brain slices from rats made epileptic by intrahippocampal tetanus toxin

1992 • 48 citations

Neuropathology of the chronic epileptic syndrome induced by intrahippocampal tetanus toxin in rat: preservation of pyramidal cells and incidence of dark cells

1992 • 48 citations

In Vitro Effect of Tetanus Toxin on GAB A Release from Rat Hippocampal Slices

1981 • 48 citations

Increased expression of GAD mRNA during the chronic epileptic syndrome due to intrahippocampal tetanus toxin

1992 • 44 citations

Memory deficits in an experimental hippocampal epileptiform syndrome in rats

1982 • 29 citations

Long-term impairment of learning ability in rats after an experimental hippocampal epileptiform syndrome

1982 • 27 citations

Ex vivo release of GABA from tetanus toxin-induced chronic epileptic foci decreased during the active seizure phase

1991 • 20 citations

Development of chronic secondary epileptic foci following intrahippocampal injection of tetanus toxin in the rat

1990 • 19 citations

Chronic Semichronic Limbic Epilepsy Produced by Microinjection of Tetanus Toxin in Cat Hippocampus

1992 • 7 citations