Crystal Structure and NMR Studies of the Apo SH2 Domains of ZAP-70: Two Bikes Rather than a Tandem

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

NMRPipe: A multidimensional spectral processing system based on UNIX pipes

1995 • 15,623 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

NMR View: A computer program for the visualization and analysis of NMR data

1994 • 3,061 citations

Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM).

1995 • 463 citations

Molecular basis for interaction of the protein tyrosine kinase ZAP-70 with the T-cell receptor

1995 • 349 citations

Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes.

1996 • 324 citations

Tandem SH2 Domains Confer High Specificity in Tyrosine Kinase Signaling

1998 • 226 citations

Structural basis for syk tyrosine kinase ubiquity in signal transduction pathways revealed by the crystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide

1998 • 222 citations

ZAP-70 binding specificity to T cell receptor tyrosine-based activation motifs: the tandem SH2 domains of ZAP-70 bind distinct tyrosine-based activation motifs with varying affinity.

1995 • 196 citations

Differential Requirements for ZAP-70 in TCR Signaling and T Cell Development

1998 • 122 citations

T Cell Development and T Cell Responses in Mice with Mutations Affecting Tyrosines 292 or 315 of the Zap-70 Protein Tyrosine Kinase

2001 • 54 citations

Requirement for Tyrosine Residues 315 and 319 within ζ Chain–Associated Protein 70 for T Cell Development

2001 • 36 citations

Anti-peptide Antibodies Detect Conformational Changes of the Inter-SH2 Domain of ZAP-70 Due to Binding to the ζ Chain and to Intramolecular Interactions

1998 • 22 citations

Interaction between the SH2 Domains of ZAP-70 and the Tyrosine-Based Activation Motif 1 Sequence of the ζ Subunit of the T-Cell Receptor

1997 • 18 citations

Role of the Src homology 2 domains and interdomain regions in ZAP‐70 phosphorylation and enzymatic activity

1999 • 9 citations