Serotonergic functions in arousal and motor activity

Raphe unit activity in freely moving cats: Correlation with level of behavioral arousal

1979 • 809 citations

Differential behavioral and neurochemical effects following lesions of the dorsal or median raphe nuclei in rats

1974 • 334 citations

Effects of enantiomers of MDA, MDMA and related analogues on [3H]serotonin and [3H]dopamine release from superfused rat brain slices

1986 • 312 citations

Behavioral studies following lesions of the mesolimbic and mesostriatal serotonergic pathways

1976 • 311 citations

In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain

1987 • 301 citations

Multivariate assessment of locomotor behavior: Pharmacological and behavioral analyses

1986 • 214 citations

Serotonin release contributes to the locomotor stimulant effects of 3,4-methylenedioxymethamphetamine in rats.

1990 • 194 citations

Derivatives of 1-(1,3-benzodioxol-5-yl)-2-butanamine: representatives of a novel therapeutic class

1986 • 187 citations

The effect of para-chlorophenylalanine on spontaneous locomotor activity in the rat

1971 • 159 citations

Drug discrimination studies with MDMA and amphetamine

1988 • 148 citations

Behavioral effects of 5,7-dihydroxytryptamine lesions of ascending 5-hydroxytryptamine pathways

1976 • 143 citations

Hallucinogens: Neurochemical, Behavioral, and Clinical Perspectives

1985 • 137 citations

SOME BEHAVIORAL EFFECTS OF SEROTONIN DEPLETION DEPEND ON METHOD: A COMPARISON OF 5,7‐DIHYDROXYTRYPTAMINE, p‐CHLOROPHENYLALANINE, p‐CHLOROAMPHETAMINE, AND ELECTROLYTIC RAPHE LESIONS*

1978 • 134 citations

Pharmacological analysis of the behavioural and thermoregulatory effects of the putative 5-HT1 receptor agonist, RU 24969, in the rat

1986 • 127 citations

Stimulant and hallucinogenic behavioral profiles of 3,4-methylenedioxymethamphetamine and N-ethyl-3,4-methylenedioxyamphetamine in rats.

1988 • 123 citations

5-Hydroxytryptamine uptake blockers attenuate the 5-hydroxytryptamine-releasing effect of 3,4-methylenedioxymethamphetamine and related agents

1990 • 106 citations

5HT-2 mediation of acute behavioral effects of hallucinogens in rats

1990 • 99 citations

Serotonin 5-HT1-like receptors mediate hyperactivity in rats induced by 3,4-methylenedioxymethamphetamine.

1992 • 93 citations

Raphe unit activity in freely moving cats is altered by manipulations of central but not peripheral motor systems

1983 • 93 citations

Serotonin1B Receptor Activation Mimics Behavioral Effects of Presynaptic Serotonin Release

1993 • 93 citations

3,4-Methylenedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine

1991 • 91 citations

Pharmacological Studies on the Serotoninergic and Nonserotonin-Mediated Stimulation of Prolactin and Corticosterone Secretion by Fenfluramine

1985 • 78 citations

Amphetamine derivatives induce locomotor hyperactivity by acting as indirect serotonin agonists

1991 • 73 citations

The effects of MDMA and other methylenedioxy-substituted phenylalkylamines on the structure of rat locomotor activity.

1992 • 72 citations

Tolerance and cross-tolerance to the activating effects of 3,4-methylenedioxymethamphetamine and a 5-hydroxytryptamine1B agonist.

1992 • 66 citations

Effects of 5HT-1A agonists on locomotor and investigatory behaviors in rats differ from those of hallucinogens

1989 • 61 citations

Tolerance to the serotonin 5-HT1 agonist RU 24969 and effects on dopaminergic behaviour

1987 • 59 citations

A proposed animal model for hallucinogens based on LSD's effects on patterns of exploration in rats.

1985 • 59 citations

Hallucinogens, neurochemical, behavioral, and clinical perspectives

1984 • 58 citations

Effects of serotonergic lesions on investigatory responding by rats in a holeboard

1980 • 58 citations

A proposed animal model for hallucinogens based on LSD's effects on patterns of exploration in rats.

1985 • 54 citations

Depletion of brain serotonin by 5,7-dihydroxytryptamine alters the response to amphetamine and the habituation of locomotor activity in rats

1985 • 53 citations

Distinct functions for dopamine and serotonin in locomotor behaviour: Evidence using the 5-HT1 agonist RU 24969 in globus pallidus-lesioned rats

1986 • 51 citations

Effects of fluoxetine ord-fenfluramine on serotonin release from, and levels in, rat frontal cortex

1990 • 50 citations

Serotonin depletion causes long-term reduction of exploration in the rat

1992 • 47 citations

Dreams and hallucinations: A common neurochemical mechanism mediating their phenomenological similarities

1978 • 46 citations

Central nervous system effects of fenfluramine hydrochloride.

1972 • 39 citations

The relation of central 5-HT1A and 5-HT2 receptors: Low dose agonist-induced selective tolerance in the rat

1991 • 35 citations

Cross-tolerance studies of serotonin receptors involved in behavioral effects of LSD in rats

1994 • 26 citations

Suppression of behavioral activity by norfenfluramine and related drugs in rats is not mediated by serotonin release

1993 • 20 citations

Fenfluramine-induced suppression of food intake and locomotor activity is differentially altered by the selective type A monoamine oxidase inhibitor clorgyline

1988 • 20 citations

Behavioral characterization of alpha-ethyltryptamine, a tryptamine derivative with MDMA-like properties in rats

1993 • 18 citations

Serotonin receptor involvement in an animal model of the acute effects of hallucinogens.

1994 • 12 citations

The Biochemistry of Mental Disorders

1974 • 12 citations

Biochemistry of mental disorders

1970 • 11 citations

Serotonin Receptor Involvement in an Animal Model of the Acute Effects of Hallucinogens

1994 • 5 citations