Oncogenic potential of cyclin E in T-cell lymphomagenesis in transgenic mice: evidence for cooperation between cyclin E and Ras but not Myc

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Principles of CDK regulation

1995 • 3,267 citations

Inhibitors of mammalian G1 cyclin-dependent kinases.

1995 • 3,258 citations

Mammalian G1 cyclins

1993 • 1,990 citations

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.

1994 • 1,970 citations

New functional activities for the p21 family of CDK inhibitors.

1997 • 1,414 citations

Human Cyclin E, a Nuclear Protein Essential for the G₁-to-S Phase Transition

1995 • 1,132 citations

Formation and Activation of a Cyclin E-cdk2 Complex During the G ₁ Phase of the Human Cell Cycle

1992 • 1,046 citations

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta.

1995 • 959 citations

Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G₁/S-Regulatory Genes

1995 • 910 citations

lnterleukin-2-mediated elimination of the p27Kipl cyclin-dependent kinase inhibitor prevented by rapamycin

1994 • 903 citations

Association of human cyclin E with a periodic G1-S phase protein kinase

1992 • 900 citations

Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family

1991 • 656 citations

Regulation of the cyclin E gene by transcription factor E2F1.

1995 • 634 citations

Redundant cyclin overexpression and gene amplification in breast cancer cells.

1993 • 526 citations

Differential Phosphorylation of the Retinoblastoma Protein by G1/S Cyclin-dependent Kinases

1997 • 486 citations

Different Roles for Cyclins D1 and E in Regulation of the G₁-to-S Transition

1995 • 469 citations

Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice.

1994 • 432 citations

Cdk inhibitors in development and cancer

1996 • 410 citations

The retinoblastoma protein pathway and the restriction point

1996 • 392 citations

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

1997 • 381 citations

Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice

1995 • 273 citations

The restriction point and control of cell proliferation

1997 • 253 citations

Induction of Mammary Gland Hyperplasia and Carcinomas in Transgenic Mice Expressing Human Cyclin E

1997 • 246 citations

E2F and Cell Proliferation: A World Turned Upside Down

1996 • 234 citations

Cyclin E in human cancers

1999 • 212 citations

Cyclin E and c-Myc promote cell proliferation in the presence of p16INK4a and of hypophosphorylated retinoblastoma family proteins

1997 • 206 citations

Human cyclin D1 encodes a labile nuclear protein whose synthesis is directly induced by growth factors and suppressed by cyclic AMP

1993 • 157 citations

Transgenic expression of human MGMT protects against azoxymethane-induced aberrant crypt foci and G to A mutations in the K-ras oncogene of mouse colon

1995 • 130 citations

Expression of a Pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/lpr mice.

1993 • 121 citations

Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells

1998 • 89 citations

Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with β-selection

1998 • 83 citations

Rapid repair of O6-methylguanine-DNA adducts protects transgenic mice from N-methylnitrosourea-induced thymic lymphomas.

1994 • 66 citations

Overexpression of cyclin E in the HC11 mouse mammary epithelial cell line is associated with growth inhibition and increased expression of p27(Kip1).

1996 • 60 citations

Malignant transformation by cyclin E and Ha-Ras correlates with lower sensitivity towards induction of cell death but requires functional Myc and CDK4

1997 • 50 citations

IgH enhancer deregulated expression of L-myc: abnormal T lymphocyte development and T cell lymphomagenesis.

1990 • 41 citations

Expression of Cyclin E and the Cyclin-Dependent Kinase Inhibitor p27 in Malignant Lymphomas—Prognostic Implications

1998 • 16 citations

N‐methylnitrosourea—lnduced Ki‐ras codon 12 mutations: Early events in mouse thymic lymphomas

1995 • 15 citations

Multistage carcinogenesis in murine thymocytes: involvement of oncogenes, chromosomal imbalances and T cell growth factor receptor.

1989 • 10 citations