IDENTIFICATION OF A COMMON RECEPTOR FOR THREE TYPES OF RAT CYTOKINE-INDUCED NEUTROPHIL CHEMOATTRACTANTS (CINCS)

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Interleukin-8 and related chemotactic cytokines--CXC and CC chemokines.

1994 • 2,251 citations

lnterleukin-8 and Related Chemotactic Cytokines—CXC and CC Chemokines

1993 • 1,650 citations

Structure and Functional Expression of a Human Interleukin-8 Receptor

1991 • 1,088 citations

Cloning of Complementary DNA Encoding a Functional Human Interleukin-8 Receptor

1991 • 878 citations

Neutrophil and B Cell Expansion in Mice That Lack the Murine IL-8 Receptor Homolog

1994 • 666 citations

Chemoattractant signaling and leukocyte activation

1995 • 510 citations

Characterization of two high affinity human interleukin-8 receptors.

1992 • 435 citations

The CXC Chemokines Growth-regulated Oncogene (GRO) α, GROβ, GROγ, Neutrophil-activating Peptide-2, and Epithelial Cell-derived Neutrophil-activating Peptide-78 Are Potent Agonists for the Type B, but Not the Type A, Human Interleukin-8 Receptor

1996 • 402 citations

Chemokine binding and activities mediated by the mouse IL-8 receptor.

1995 • 355 citations

Interleukin 8-stimulated phosphatidylinositol-3-kinase activity regulates the migration of human neutrophils independent of extracellular signal-regulated kinase and p38 mitogen-activated protein kinases

1997 • 314 citations

The murine interleukin 8 type B receptor homologue and its ligands. Expression and biological characterization.

1994 • 262 citations

The neutrophil chemoattractant produced by the rat kidney epithelioid cell line NRK-52E is a protein related to the KC/gro protein

1989 • 234 citations

Direct stimulation of Bruton's tyrosine kinase by Gq-protein α-subunit

1997 • 186 citations

The G protein Gα12 stimulates Bruton's tyrosine kinase and a rasGAP through a conserved PH/BM domain

1998 • 183 citations

Differential usage of the CXC chemokine receptors 1 and 2 by interleukin‐8, granulocyte chemotactic protein‐2 and epithelial‐cell‐derived neutrophil attractant‐78

1998 • 161 citations

Both interleukin‐8 receptors independently mediate chemotaxis

1994 • 145 citations

The murine homolog of the interleukin-8 receptor CXCR-2 is essential for the occurrence of neutrophilic inflammation in the air pouch model of acute urate crystal-induced gouty synovitis

1998 • 144 citations

Identification of cytokine-induced neutrophil chemoattractants (CINC), rat GRO/CINC-2α and CINC-2 β, produced by granulation tissue in culture: purification, complete amino acid sequences and characterization

1994 • 121 citations

Chemoattractant Receptors Activate Distinct Pathways for Chemotaxis and Secretion

1999 • 99 citations

Identification of Two Rat Genes Orthologous to the Human Interleukin-8 Receptors

1996 • 75 citations

Recombinant Production and Biological Properties of Rat Cytokine‐Induced Neutrophil Chemoattractants, GRO/CINC‐2α, CINC‐2β and CINC‐3

1995 • 71 citations

Signal transduction pathway in human polymorphonuclear leukocytes for chemotaxis induced by a chemotactic factor. Distinct from the pathway for superoxide anion production.

1994 • 64 citations

Diverging Signal Transduction Pathways Activated by Interleukin 8 (IL-8) and Related Chemokines in Human Neutrophils

1996 • 60 citations

Recombinant Production and Biological Properties of Rat Cytokine-Induced Neutrophil Chemoattractants, GRO/CINC-2alpha, CINC-2beta and CINC-3

1995 • 50 citations

Inhibition of acute peritoneal inflammation in rats by a cytokine-induced neutrophil chemoattractant receptor antagonist.

1997 • 32 citations

GENE STRUCTURE, cDNA CLONING, AND EXPRESSION OF THE RAT CYTOKINE-INDUCED NEUTROPHIL CHEMOATTRACTANT-2 (CINC-2) GENE

1998 • 26 citations

Identification and Characterization of Receptor for Cytokine-Induced Neutrophil Chemoattractant-3 on Rat Neutrophils

1997 • 15 citations

Rat macrophage inflammatory protein-1alpha, a CC chemokine, acts as a neutrophil chemoattractant in vitro and in vivo.

1999 • 11 citations

Molecular cloning and characterization of a cDNA encoding the rat interleukin-8 receptor1The sequence data reported in this paper have been submitted to the EMBL and NCBI databases under the accession number X77797.1

1997 • 7 citations

Evidence for Two Putative Receptors Mediating Chemotactic Activity of Cytokine-Induced Neutrophil Chemoattractants (CINCs) for Rat Neutrophils.

1996 • 6 citations