The Drosophila takeout Gene Is a Novel Molecular Link between Circadian Rhythms and Feeding Behavior

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Basic local alignment search tool

1990 • 87,358 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Positional cloning of the mouse obese gene and its human homologue

1994 • 12,975 citations

Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites

1997 • 5,415 citations

Molecular Bases for Circadian Clocks

1999 • 2,823 citations

The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene

1999 • 2,583 citations

Clock Mutants of Drosophila melanogaster

1971 • 2,191 citations

A Serum Shock Induces Circadian Gene Expression in Mammalian Tissue Culture Cells

1998 • 1,954 citations

The lipocalin protein family: structure and function

1996 • 1,658 citations

A pdf Neuropeptide Gene Mutation and Ablation of PDF Neurons Each Cause Severe Abnormalities of Behavioral Circadian Rhythms in Drosophila

1999 • 1,122 citations

A Molecular Mechanism Regulating Rhythmic Output from the Suprachiasmatic Circadian Clock

1999 • 894 citations

Positional Syntenic Cloning and Functional Characterization of the Mammalian Circadian Mutation tau

2000 • 850 citations

double-time Is a Novel Drosophila Clock Gene that Regulates PERIOD Protein Accumulation

1998 • 820 citations

Extended Life-Span and Stress Resistance in the Drosophila Mutant methuselah

1998 • 815 citations

Closing the Circadian Loop: CLOCK-Induced Transcription of Its Own Inhibitors per and tim

1998 • 799 citations

A diffusible coupling signal from the transplanted suprachiasmatic nucleus controlling circadian locomotor rhythms

1996 • 776 citations

A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless

1998 • 718 citations

The Drosophila Clock Gene double-time Encodes a Protein Closely Related to Human Casein Kinase Iε

1998 • 678 citations

CYCLE Is a Second bHLH-PAS Clock Protein Essential for Circadian Rhythmicity and Transcription of Drosophila period and timeless

1998 • 631 citations

Loss of Circadian Behavioral Rhythms and per RNA Oscillations in the Drosophila Mutant timeless

1994 • 627 citations

Chromosomal walking and jumping to isolate DNA from the Ace and rosy loci and the bithorax complex in Drosophila melanogaster

1983 • 626 citations

Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function.

1998 • 625 citations

Transport and Storage of Vitamin A

1990 • 618 citations

Biology of Drosophila

1950 • 565 citations

Differential regulation of circadian pacemaker output by separate clock genes in Drosophila

2000 • 531 citations

A light-entrainment mechanism for the Drosophila circadian clock

1996 • 471 citations

Cycling vrille Expression Is Required for a Functional Drosophila Clock

1999 • 433 citations

CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP

2000 • 418 citations

Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms

1984 • 409 citations

Adrenergic signals direct rhythmic expression of transcriptional represser CREM in the pineal gland

1993 • 394 citations

Rhythmic Expression of timeless : A Basis for Promoting Circadian Cycles in period Gene Autoregulation

1995 • 368 citations

Isolation of timeless by PER Protein Interaction: Defective Interaction Between timeless Protein and Long-Period Mutant PER ^L

1995 • 364 citations

Circadian rhythms in olfactory responses of Drosophila melanogaster

1999 • 316 citations

Crystallographic refinement of human serum retinol binding protein at 2Å resolution

1990 • 310 citations

Homology of β-Lactoglobulin, Serum Retinol-Binding Protein, and Protein HC

1985 • 260 citations

Post-transcriptional regulation contributes to Drosophila clock gene mRNA cycling

1997 • 257 citations

Molecular Cloning of Genes Under Control of the Circadian Clock in Neurospora

1989 • 235 citations

The Drosophila CLOCK Protein Undergoes Daily Rhythms in Abundance, Phosphorylation, and Interactions with the PER–TIM Complex

1998 • 231 citations

Molecular genetics of a biological clock in Drosophila

1984 • 230 citations

Transplantation of a circadian pacemaker in Drosophila

1979 • 172 citations

Circadian Expression of the Steroid 15 α-Hydroxylase (Cyp2a4) and Coumarin 7-Hydroxylase (Cyp2a5) Genes in Mouse Liver Is Regulated by the PAR Leucine Zipper Transcription Factor DBP

1999 • 163 citations

Effect of constant light and circadian entrainment of perS flies: evidence for light-mediated delay of the negative feedback loop in Drosophila.

1996 • 121 citations

Drosophila homologs of two mammalian intracellular Ca2+-release channels: identification and expression patterns of the inositol 1,4,5- triphosphate and the ryanodine receptor genes

1992 • 116 citations

Melatonin's Role in Vertebrate Orcadian Rhythms

1998 • 115 citations

A Molecular Rhythm Mediating Circadian Clock Output in Drosophila

1998 • 107 citations

Arginine vasopressin: a novel peptide rhythm in cerebrospinal fluid

1987 • 107 citations

Coexpression of two odorant-binding protein homologs in Drosophila: implications for olfactory coding.

1997 • 104 citations

The tim Mutant of the Drosophila Rhythm Gene timeless Manifests Allele-Specific Interactions with period Gene Mutants

1996 • 103 citations

A new biological rhythm mutant of Drosophila melanogaster that identifies a gene with an essential embryonic function.

1993 • 101 citations

Rabbit muscle phosphorylase phosphatase. 1. Purification and chemical properties

1977 • 97 citations

Odorant Binding by a Pheromone Binding Protein: Active Site Mapping by Photoaffinity Labeling

1994 • 81 citations

Coexpression of Two Odorant-Binding Protein Homologs inDrosophila: Implications for Olfactory Coding

1997 • 79 citations

Ligand binding by a recombinant insect juvenile hormone binding protein

1993 • 78 citations

A new gene encoding a putative transcription factor regulated by the Drosophila circadian clock

1997 • 64 citations

A novel circadianly expressed Drosophila melanogaster gene dependent on the period gene for its rhythmic expression.

1996 • 59 citations

Expression of a Drosophila mRNA is under circadian clock control during pupation

1989 • 59 citations

Key Disulfide Bonds in an Insect Hormone Binding Protein: cDNA Cloning of a Juvenile Hormone Binding Protein of Heliothis virescens and Ligand Binding by Native and Mutant Forms

1995 • 57 citations

Binding site mapping of a photoaffinity-labeled juvenile hormone binding protein

1992 • 38 citations

Regulation of thevgf gene in the golden hamster suprachiasmatic nucleus by light and by the circadian clock

1997 • 37 citations

Olfactory Sensitivity in Tsetse Flies: a Daily Rhythm

1998 • 31 citations

Advances in the molecular genetics of obesity

1999 • 8 citations