Contribution to the thermodynamics of protein folding from the reduction in water-accessible nonpolar surface area

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Some Factors in the Interpretation of Protein Denaturation

1959 • 4,817 citations

Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics

1990 • 3,683 citations

Dominant forces in protein folding

1990 • 3,682 citations

AREAS, VOLUMES, PACKING, AND PROTEIN STRUCTURE

1977 • 2,631 citations

Stability of Proteins Small Globular Proteins

1979 • 2,139 citations

Solvation energy in protein folding and binding

1986 • 1,853 citations

Turns in Peptides and Proteins

1985 • 1,658 citations

The Solubility of Amino Acids and Two Glycine Peptides in Aqueous Ethanol and Dioxane Solutions

1971 • 1,417 citations

Stability of Protein Structure and Hydrophobic Interaction

1988 • 1,293 citations

Environment and exposure to solvent of protein atoms. Lysozyme and insulin

1973 • 1,259 citations

Hydrophobicity of Amino Acid Residues in Globular Proteins

1985 • 1,168 citations

The nature of the accessible and buried surfaces in proteins

1976 • 1,151 citations

Systematic analysis of structural data as a research technique in organic chemistry

1983 • 1,035 citations

Group contributions to the thermodynamic properties of non-ionic organic solutes in dilute aqueous solution

1981 • 971 citations

Interior and surface of monomeric proteins

1987 • 924 citations

Hydrophobic bonding and accessible surface area in proteins

1974 • 887 citations

Temperature dependence of the hydrophobic interaction in protein folding.

1986 • 865 citations

Affinities of amino acid side chains for solvent water

1981 • 846 citations

Heat capacity and entropy changes in processes involving proteins.

1977 • 846 citations

Conformation of amino acid side-chains in proteins

1978 • 777 citations

Accessible surface areas as a measure of the thermodynamic parameters of hydration of peptides.

1987 • 737 citations

Hydrophobic parameters π of amino-acid side chains from the partitioning of N-acetyl-amino-acid amides.

1983 • 705 citations

Surface and inside volumes in globular proteins

1979 • 704 citations

Theory of hydrophobic bonding. II. Correlation of hydrocarbon solubility in water with solvent cavity surface area

1972 • 694 citations

Solvent accessible surface area and excluded volume in proteins

1984 • 667 citations

Surface, subunit interfaces and interior of oligomeric proteins

1988 • 644 citations

Hydrophobicity scales and computational techniques for detecting amphipathic structures in proteins

1987 • 637 citations

Reversible pressure-temperature denaturation of chymotrypsinogen

1971 • 593 citations

Common Features of Protein Unfolding and Dissolution of Hydrophobic Compounds

1990 • 435 citations

Analysis of the relationship between side-chain conformation and secondary structure in globular proteins

1987 • 422 citations

Role of the hydrophobic effect in stability of site-specific protein-DNA complexes

1989 • 380 citations

Search for a realistic view of hydrophobic effects

1990 • 378 citations

Packing of α-helices: Geometrical constraints and contact areas

1978 • 366 citations

The accessible surface area and stability of oligomeric proteins

1987 • 353 citations

Heat capacity and conformation of proteins in the denatured state

1989 • 319 citations

STRUCTURE AND DYNAMICS OF WATER SURROUNDING BIOMOLECULES

1987 • 296 citations

Hydrophobic effect in protein folding and other noncovalent processes involving proteins.

1989 • 295 citations

Internal cavities and buried waters in globular proteins

1986 • 268 citations

Thermodynamic Problems of Protein Structure

1989 • 260 citations

Water and proteins. II. The location and dynamics of water in protein systems and its relation to their stability and properties

1983 • 236 citations

A new method for determining the heat capacity change for protein folding

1989 • 197 citations

Calculation of molecular volumes and areas for structures of known geometry

1985 • 196 citations

Anomalous heat capacity of hydrophobic solvation

1985 • 195 citations

Calorimetric determination of enthalpies of solution of slightly soluble liquids II. Enthalpy of solution of some hydrocarbons in water and their use in establishing the temperature dependence of their solubilities

1976 • 191 citations

Calorimetric measurements on slightly soluble gases in water Enthalpies of solution of helium, neon, argon, krypton, xenon, methane, ethane, propane, n-butane, and oxygen at 288.15, 298.15, and 308.15 K

1984 • 111 citations

Heat of solution of methane in water from 0 to 50.degree.C

1986 • 93 citations

Partial specific heat capacity of benzene and of toluene in aqueous solution determined calorimetrically for a broad temperature range

1988 • 82 citations

Heats of solution of ethane and propane in water from 0 to 50.degree.C

1987 • 70 citations

Enthalpic and entropic contributions to actin stability: calorimetry, circular dichroism, and fluorescence study and effects of calcium

1990 • 70 citations

Thermal denaturation of staphylococcal nuclease

1985 • 57 citations

Thermodynamics of dissolution of solid cyclic dipeptides containing hydrophobic side groups

1989 • 49 citations

Haemoglobin: The surface buried between the α1β1 and α2β2 dimers in the deoxy and oxy structures

1985 • 43 citations

Calorimetric measurement of the enthalpy of dissolution of diketopiperazine in water as a function of temperature

1989 • 35 citations

Hen egg white lysozyme: carbon-13 nuclear magnetic resonance assignments and dependence of conformational flexibility on inhibitor binding and temperature

1984 • 25 citations

Ribonuclease A: carbon-13 nuclear magnetic resonance assignments, binding sites, and conformational flexibility

1984 • 21 citations

Preliminary Analysis of Water Molecule Distributions in Proteins

1989 • 6 citations