Tunable pH-Sensitive Liposomes Composed of Mixtures of Cationic and Anionic Lipids

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

Lipid polymorphism and the functional roles of lipids in biological membranes

1979 • 1,817 citations

Vesicles of variable sizes produced by a rapid extrusion procedure

1986 • 1,654 citations

Acid pH in tumors and its potential for therapeutic exploitation.

1989 • 1,633 citations

Use of resonance energy transfer to monitor membrane fusion

1981 • 1,274 citations

Spontaneous Vesicle Formation in Aqueous Mixtures of Single-Tailed Surfactants

1989 • 1,138 citations

Mechanism of DNA Release from Cationic Liposome/DNA Complexes Used in Cell Transfection^,

1996 • 1,103 citations

Rapid acidification of endocytic vesicles containing α2-macroglobulin

1982 • 672 citations

Mechanism of oligonucleotide release from cationic liposomes.

1996 • 617 citations

Nonviral Gene Therapy: The Promise of Genes as Pharmaceutical Products

1995 • 471 citations

pH-Induced destabilization of phosphatidylethanolamine-containing liposomes: role of bilayer contact

1984 • 436 citations

The polymorphic phase behaviour of phosphatidylethanolamines of natural and synthetic origin. A 31P NMR study

1978 • 416 citations

p H-Sensitive Liposomes: Possible Clinical Implications

1980 • 410 citations

Ionization of phospholipids and phospholipid-supported interfacial lateral diffusion of protons in membrane model systems

1990 • 339 citations

Delivery of plasmid DNA into mammalian cell lines using pH-sensitive liposomes: comparison with cationic liposomes.

1992 • 334 citations

Cardiolipin forms hexagonal structures with divalent cations

1972 • 325 citations

Self-Assembly of Flat Nanodiscs in Salt-Free Catanionic Surfactant Solutions

1999 • 323 citations

The Modified Stalk Mechanism of Lamellar/Inverted Phase Transitions and Its Implications for Membrane Fusion

1999 • 321 citations

Membrane fusion and inverted phases

1989 • 309 citations

Lipid Polymorphism:The Molecular Basis of Nonbilayer Phases

1985 • 285 citations

pH-sensitive liposomes: acid-induced liposome fusion.

1984 • 283 citations

Polymorphic phase behaviour of cardiolipin as detected by 31P NMR and freeze-fracture techniques. Effects of calcium, dibucaine and chlorpromazine

1978 • 208 citations

Electrostatic parameters of cationic liposomes commonly used for gene delivery as determined by 4-heptadecyl-7-hydroxycoumarin1A preliminary report of this study was presented at the 3rd annual conference: Artificial Self-Assembling Systems for Gene Delivery, organized by Cambridge Healthtec Institute, November 17–18, 1996, Coronado, CA.1

1997 • 152 citations

The lipidic particle as an intermediate structure in membrane fusion processes and bilayer to hexagonal HII transitions

1980 • 149 citations

Structural and fusogenic properties of cationic liposomes in the presence of plasmid DNA

1997 • 145 citations

Bending membranes to the task: structural intermediates in bilayer fusion

1995 • 136 citations

Effects of replacement of the hydroxyl group of cholesterol and tocopherol on the thermotropic behavior of phospholipid membranes

1985 • 110 citations

Cholesteryl hemisuccinate exhibits pH sensitive polymorphic phase behavior

2000 • 105 citations

Ca2+ and pH induced fusion of small unilamellar vesicles consisting of phosphatidylethanolamine and negatively charged phospholipids: A freeze fracture study

1983 • 96 citations

Cation-dependent segregation phenomena and phase behavior in model membrane systems containing phosphatidylserine: influence of cholesterol and acyl chain composition

1984 • 88 citations

Acid- and calcium-induced structural changes in phosphatidylethanolamine membranes stabilized by cholesteryl hemisuccinate

1985 • 74 citations

Immunoliposomes with different acid sensitivities as probes for the cellular endocytic pathway

1989 • 67 citations

[28] pH-sensitive liposomes for delivery of macromolecules into cytoplasm of cultured cells

1993 • 48 citations

pH-Sensitive liposomes composed of tocopherol hemisuccinate and of phosphatidylethanolamine including tocopherol hemisuccinate

1994 • 46 citations

Freeze‐fracture of lipids and model membrane systems

1989 • 39 citations

THE POLYMORPHIC PHASE BEHAVIOUR OF PHOSPHATIDYLETHANOLAMINES OF NATURAL AND SYNTHETIC ORIGIN

1978 • 36 citations

Effects of pH and cholesterol on DMPA membranes: a solid state 2H- and 31P-NMR study

1995 • 34 citations

Characterization of cholesterol hemisuccinate and α-tocopherol hemisucccinate vesicles

1988 • 20 citations

Äntisense nucleic acids as a potential class of pharmaceutical agents

1988 • 13 citations

Deleted Work

1955 • 0 citations