A study to determine whether trisomy 8, deleted 9q and trisomy 22 are markers of cryptic rearrangements of PML/RARα, AML1/ETO and CBFB/MYH11 respectively in acute myeloid leukaemia

Reverse transcription polymerase chain reaction for the rearranged retinoic acid receptor alpha clarifies diagnosis and detects minimal residual disease in acute promyelocytic leukemia.

1992 • 280 citations

Molecular rearrangement of the ALL-1 gene in acute myeloid leukemia without cytogenetic evidence of 11q23 chromosomal translocations.

1994 • 158 citations

Molecular detection of t(8;21)/AML1‐ETO in AML M1/M2: correlation with cytogenetics, morphology and immunophenotype

1996 • 135 citations

Establishing the presence of the t( 15; 17) in suspected acute promyelocytic leukaemia: cytogenetic, molecular and PML immunofluorescence assessment of patients entered into the M.R.C. ATRA trial

1996 • 132 citations

Detection of the chromosome 16 CBF beta-MYH11 fusion transcript in myelomonocytic leukemias

1995 • 114 citations

Incidence of AML1/ETO fusion transcripts in patients entered into the MRC AML trials

1997 • 107 citations

Secondary chromosomal abnormalities in acute leukemias.

1994 • 101 citations

Frequency of CBFβ/MYH11 fusion transcripts in patients entered into the U.K. MRC AML trials

1997 • 93 citations

Correlation between cell morphology and expression of the AML1/ETO chimeric transcript in patients with acute myeloid leukemia without the t(8;21).

1994 • 85 citations

Interstitial insertion of retinoic acid receptor-alpha gene in acute promyelocytic leukemia with normal chromosomes 15 and 17

1994 • 83 citations

Impact of diagnostic cytogenetics on outcome in AML: Analysis of 1,613 patients entered into the UK MRC AML 10 trial.

1996 • 10 citations

Deleted Work

1955 • 0 citations