Cardiolipin Biosynthesis and Mitochondrial Respiratory Chain Function Are Interdependent

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

Current Protocols in Molecular Biology

1989 • 1,916 citations

The biosynthesis and functional role of cardiolipin

2000 • 786 citations

Cardiolipin Stabilizes Respiratory Chain Supercomplexes

2003 • 783 citations

Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis

2000 • 728 citations

Cardiolipins and biomembrane function

1992 • 597 citations

Specific roles of protein-phospholipid interactions in the yeast cytochrome bc1 complex structure

2001 • 436 citations

Absence of Cardiolipin in the crd1 Null Mutant Results in Decreased Mitochondrial Membrane Potential and Reduced Mitochondrial Function

2000 • 409 citations

Cardiolipin requirement for electron transfer in complex I and III of the mitochondrial respiratory chain.

1981 • 389 citations

Genome-wide Responses to Mitochondrial Dysfunction

2001 • 387 citations

Role of reactive oxygen species and cardiolipin in the release of cytochrome c from mitochondria

2003 • 376 citations

Defective Remodeling of Cardiolipin and Phosphatidylglycerol in Barth Syndrome

2000 • 369 citations

ADP/ATP carrier protein from beef heart mitochondria has high amounts of tightly bound cardiolipin, as revealed by phosphorus-31 nuclear magnetic resonance

1985 • 296 citations

Acetyl- <scp>l</scp> -carnitine fed to old rats partially restores mitochondrial function and ambulatory activity

1998 • 264 citations

Saturated Fatty Acid-induced Apoptosis in MDA-MB-231 Breast Cancer Cells

2003 • 257 citations

Evidence for two distinct acidic phospholipid-binding sites in cytochrome c.

1994 • 254 citations

Structural details of an interaction between cardiolipin and an integral membrane protein

1999 • 233 citations

Tightly associated cardiolipin in the bovine heart mitochondrial ATP synthase as analyzed by 31P nuclear magnetic resonance spectroscopy.

1990 • 231 citations

Isolation and Characterization of the Gene (CLS1 ) Encoding Cardiolipin Synthase in Saccharomyces cerevisiae

1998 • 212 citations

The PEL1 Gene (Renamed PGS1) Encodes the Phosphatidylglycero-phosphate Synthase ofSaccharomyces cerevisiae

1998 • 206 citations

Subcellular and submitochondrial localization of phospholipid-synthesizing enzymes in Saccharomyces cerevisiae

1986 • 204 citations

On the Structure of Cardiolipin^*

1964 • 202 citations

Yeast mutants auxotrophic for choline or ethanolamine

1980 • 182 citations

Cardiolipin is not essential for the growth of Saccharomyces cerevisiae on fermentable or non‐fermentable carbon sources

1997 • 182 citations

Loss of cardiolipin and mitochondria during programmed neuronal death: evidence of a role for lipid peroxidation and autophagy

2002 • 170 citations

Cardiolipin is synthesized on the matrix side of the inner membrane in rat liver mitochondria.

1993 • 161 citations

YDL142c encodes cardiolipin synthase (Cls1p) and is non-essential for aerobic growth ofSaccharomyces cerevisiae

1998 • 151 citations

Phospholipase A₂ Digestion of Cardiolipin Bound to Bovine Cytochrome c Oxidase Alters Both Activity and Quaternary Structure^†

1999 • 150 citations

Phospholipase Digestion of Bound Cardiolipin Reversibly Inactivates Bovine Cytochrome bc₁

1999 • 149 citations

Cardiolipin prevents rate-dependent uncoupling and provides osmotic stability in yeast mitochondria

2002 • 139 citations

The mitochondrial phosphate carrier has an essential requirement for cardiolipin

1982 • 139 citations

Études sur le chondriome de la levure

1962 • 137 citations

Oxidative phosphorylation in cardiolipin-lacking yeast mitochondria

2000 • 126 citations

Cardiolipin-depleted bovine heart cytochrome c oxidase: binding stoichiometry and affinity for cardiolipin derivatives

1990 • 126 citations

Études sur le chondriome de la levure: I. Variation de l'ultrastructure du chondriome au cours du cycle de la croissance aérobie

1962 • 115 citations

Thin-layer chromatography of human platelet phospholipids with fatty acid analysis

1987 • 114 citations

Specific Cardiolipin Binding Interferes with Labeling of Sulfhydryl Residues in the Adenosine Diphosphate/Adenosine Triphosphate Carrier Protein from Beef Heart Mitochondria

1996 • 100 citations

Direct Cardiolipin Assay in Yeast Using the Red Fluorescence Emission of 10-N-Nonyl Acridine Orange

1995 • 100 citations

Phospholipid specificity of bovine heart bc₁ complex

1990 • 97 citations

CARDIOLIPIN CONTENT OF WILD TYPE AND MUTANT YEASTS IN RELATION TO MITOCHONDRIAL FUNCTION AND DEVELOPMENT

1971 • 95 citations

The effect of aging and acetyl‐L‐carnitine on the pyruvate transport andoxidation in rat heart mitochondria

1999 • 85 citations

Direct Cardiolipin Assay in Yeast Using the Red Fluorescence Emission of 10-N-Nonyl Acridine Orange

1995 • 84 citations

Cardiolipin synthase from mammalian mitochondria

1997 • 77 citations

Biochemical characterization and regulation of cardiolipin synthase in Saccharomyces cerevisiae

1990 • 69 citations

Asymmetrical distribution of cardiolipin in yeast inner mitochondrial membrane triggered by carbon catabolite repression

1997 • 68 citations

Structural role of phospholipids in ubiquinol-cytochrome c reductase

1980 • 68 citations

Cardiolipin synthase expression is essential for growth at elevated temperature and is regulated by factors affecting mitochondrial development

1999 • 62 citations

Solubilization, purification, and characterization of cardiolipin synthase from rat liver mitochondria. Demonstration of its phospholipid requirement.

1991 • 60 citations

Phosphatidylglycerolphosphate synthase encoded by the PEL1/PGS1 gene in Saccharomyces cerevisiae is localized in mitochondria and its expression is regulated by phospholipid precursors

1998 • 53 citations

Interactions of phospholipids with the mitochondrial cytochrome‐c reductase studied by spin‐label ESR and NMR spectroscopy

1992 • 49 citations

Carbon Source Regulation of PIS1 Gene Expression in Saccharomyces cerevisiae Involves the MCM1 Gene and the Two-component Regulatory Gene, SLN1

1996 • 45 citations

Regulation of phosphatidylglycerolphosphate synthase in Saccharomyces cerevisiae by factors affecting mitochondrial development

1991 • 42 citations

Ionophores and intact cells I. Valinomycin and nigericin act preferentially on mitochondria and not on the plasma membrane of Saccharomyces cerevisiae

1982 • 39 citations

Biosynthesis of Cardiolipin in Plant Mitochondria

1994 • 35 citations

Interaction of phospholipids with the detergent-solubilized ADP/ATP carrier protein as studied by spin-label electron spin resonance

1988 • 35 citations

Regulation of Phosphatidylglycerophosphate Synthase by Inositol in Saccharomyces cerevisiae Is Not at the Level of PGS1 mRNA Abundance

2003 • 34 citations

Cardiolipin Synthase Is Associated with a Large Complex in Yeast Mitochondria

1998 • 30 citations

The yeast ATP synthase subunit 4: structure and function

1989 • 14 citations