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Phase I clinical trial of combined therapy with 5-FU (NSC 19893) and cis-platinum (II) diaminedichloride (NSC 119875)

Data up to Jan 2025

Published1974
Citations20
References18

Total Citations Per Year

Abstract

References (18)

Platinum Compounds: a New Class of Potent Antitumour Agents

1969 • 3,785 citations

Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode

1965 • 2,890 citations

The Inhibition of Growth or Cell Division in Escherichia coli by Different Ionic Species of Platinum(IV) Complexes

1967 • 405 citations

The successful regression of large solid sarcoma 180 tumors by platinum compounds.

1970 • 372 citations

Inhibitory effects of anti‐tumor platinum compounds on DNA, RNA and protein syntheses in mammalian cells in vitro

1970 • 372 citations

CIS-dichlorodiammineplatinum (II)

1970 • 284 citations

Cross-linking of Complementary Strands of DNA in Mammalian Cells by Antitumour Platinum Compounds

1972 • 245 citations

Preliminary clinical experience withcis-diamminedichloroplatinum (II) (NSC 119875, CACP)

1972 • 168 citations

Antileukaemic and Nephrotoxic Properties of Platinum Compounds

1971 • 113 citations

Acute toxicologic and pathologic effects of cis-diamminedichloroplatinum (NSC-119875) in the male rat.

1971 • 106 citations

The interaction of platinum II compounds with bacteriophages T7 and R17

1972 • 97 citations

Inhibition of Dunning asc itic leukemia and Walker 256 carcinosarcoma with cis-diamminedichloroplatinum (NSC-119875).

1970 • 62 citations

Growth Inhibition of Rat Mammary Carcinoma Induced by Cis-Platinum Diamminodichloride-II<xref ref-type="fn" rid="FN1">2</xref><xref ref-type="fn" rid="FN2">3</xref>

1971 • 46 citations

Cis-Dichlorodiammineplatinum [II]: Inhibition of Nucleic Acid Synthesis in Lymphocytes Stimulated with Phytohemagglutinin

1971 • 43 citations

Antitumor and antimitogenic properties of cis-dichloro(dipyridine)platinum(II).

1971 • 30 citations

Chemotherapy of a mouse reticulum cell sarcoma with platinum salts. Abstr.

1970 • 18 citations

Enhanced survival response of l1210 leukemic mice to a single combin- ation treatment with cis-platinum(ii) diamminodichloride (cis-pt ii. Nsc-119875) plus cyclophosphamide (cy, nsc-26271). Abstr.

1971 • 6 citations

Further clinical studies of 5-fluorouracil (5-FU; NSC-19893) given by the multiple daily dose method in disseminated breast cancer.

1973 • 6 citations

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Phase I clinical trial of combined therapy with 5-FU (NSC 19893) and cis-platinum (II)… (1974) – Cancer | Metascience Observatory Explorer