Sildenafil Improves Exercise Hemodynamics and Oxygen Uptake in Patients With Systolic Heart Failure

A new method for detecting anaerobic threshold by gas exchange

1986 • 3,936 citations

Effect of Vasodilator Therapy on Mortality in Chronic Congestive Heart Failure

1986 • 2,409 citations

Principles of Exercise Testing and Interpretation.

1987 • 2,278 citations

Intravenous Nesiritide, a Natriuretic Peptide, in the Treatment of Decompensated Congestive Heart Failure

2000 • 890 citations

Contribution of skeletal muscle atrophy to exercise intolerance and altered muscle metabolism in heart failure.

1992 • 740 citations

Skeletal muscle biochemistry and histology in ambulatory patients with long-term heart failure.

1990 • 693 citations

Preserved right ventricular ejection fraction predicts exercise capacity and survival in advanced heart failure

1995 • 684 citations

Oral Sildenafil Is an Effective and Specific Pulmonary Vasodilator in Patients With Pulmonary Arterial Hypertension

2002 • 589 citations

Randomised trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary oedema

1998 • 567 citations

Intravenous Nesiritide, a Natriuretic Peptide, in the Treatment of Decompensated Congestive Heart Failure

2000 • 542 citations

Cardiopulmonary exercise testing for prognosis in chronic heart failure: continuous and independent prognostic value from VE/VCO2slope and peak VO2

2000 • 512 citations

Secondary Pulmonary Hypertension in Chronic Heart Failure

2000 • 408 citations

Overall cardiovascular profile of sildenafil citrate

1999 • 313 citations

Acute type 5 phosphodiesterase inhibition with sildenafil enhances flow-mediated vasodilation in patients with chronic heart failure

2000 • 306 citations

Cardiovascular effects of inhaled nitric oxide in patients with left ventricular dysfunction.

1994 • 248 citations

The effects of phosphodiesterase-5 inhibition with sildenafil on pulmonary hemodynamics and diffusion capacity, exercise ventilatory efficiency, and oxygen uptake kinetics in chronic heart failure

2004 • 229 citations

Hemodynamic effects of inhaled nitric oxide in heart failure

1994 • 204 citations

Hemodynamic Effects of Sildenafil in Patients With Congestive Heart Failure and Pulmonary Hypertension

2005 • 201 citations

Inhaled nitric oxide leading to pulmonary edema in stable severe heart failure

1994 • 187 citations

Identification of PDE isozymes in human pulmonary artery and effect of selective PDE inhibitors

1994 • 182 citations

Sildenafil Effects on Exercise, Neurohormonal Activation, and Erectile Dysfunction in Congestive Heart Failure

2002 • 182 citations

Effect of sildenafil on the acute pulmonary vasodilator response to inhaled nitric oxide in adults with primary pulmonary hypertension

2002 • 171 citations

Inhibition of cyclic 3'-5'-guanosine monophosphate-specific phosphodiesterase selectively vasodilates the pulmonary circulation in chronically hypoxic rats.

1996 • 170 citations

Pulmonary versus systemic hemodynamics in determining exercise capacity of patients with chronic left ventricular failure

1985 • 150 citations

Development of an assay for the simultaneous determination of sildenfail (viagra) and its metabolite (UK-103,320) using automated sequential trace enrichment of dialysates and high-performance liquid chromatography

1997 • 108 citations

Cl- current activation in choroid plexus epithelial cells involves a G protein and protein kinase A

1994 • 87 citations

Simultaneous assay of sildenafil and desmethylsildenafil in human plasma using liquid chromatography–tandem mass spectrometry on silica column with aqueous–organic mobile phase

2002 • 83 citations

Chronic hypoxia attenuates cGMP-dependent pulmonary vasodilation

2002 • 47 citations

Critical capillary oxygen partial pressure and lactate threshold in patients with cardiovascular disease

1994 • 42 citations

Influences of sildenafil on lung function and hemodynamics in patients with chronic heart failure

2004 • 41 citations

Inhaled nitric oxide improves exercise capacity in patients with severe heart failure and right ventricular dysfunction

1998 • 37 citations

Some Recent Advances in Studies on J Receptors

1995 • 35 citations