Role of oxygen radicals and arachidonic acid metabolites in the reverse passive Arthus reaction and carrageenin paw oedema in the rat

Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker

1982 • 3,566 citations

Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions.

1982 • 1,241 citations

Leukotrienes and Other Products of the 5-Lipoxygenase Pathway

1990 • 1,216 citations

Control of vascular permeability by polymorphonuclear leukocytes in inflammation

1981 • 850 citations

Free radicals and inflammation: superoxide-dependent activation of a neutrophil chemotactic factor in plasma.

1980 • 628 citations

Modulation of acute inflammation by endogenous nitric oxide

1992 • 543 citations

Synthesis of nitric oxide from <scp>l</scp>-arginine by neutrophils. Release and interaction with superoxide anion

1989 • 529 citations

Role of prostaglandin-mediated vasodilatation in inflammation

1977 • 511 citations

A new approach to anti-inflammatory drugs

1979 • 501 citations

Anti-inflammatory glucocorticoids inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat

1990 • 389 citations

L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor

1989 • 337 citations

Evidence that endogenous nitric oxide modulates oedema formation induced by substance P

1990 • 201 citations

Participation of superoxide anions at the prostaglandin phase of carrageenan foot-oedema

1976 • 153 citations

Oxidant injury of cells.

1987 • 135 citations

Eicosanoids in inflammation.

1984 • 133 citations

Eicosanoids and inflammation

1988 • 122 citations

Inhibition of arachidonic acid cyclo-oxygenase and lipoxygenase activities of leukocytes by indomethacin and compound BW755C

1980 • 121 citations

Suppression by superoxide dismutase of immune-complex--induced pulmonary alveolitis and dermal inflammation.

1981 • 100 citations

Studies of leukotriene B4-specific binding and function in rat polymorphonuclear leukocytes: absence of a chemotactic response.

1985 • 92 citations

Evidence for a role of hydroxyl radical in immune-complex-induced vasculitis.

1984 • 88 citations

Mechanisms of endothelial cell injury.

1991 • 87 citations

Oxidation of phenidone and BW755C by prostaglandin endoperoxide synthetase.

1982 • 69 citations

Role of O2− in neutrophil recruitment into sites of dermal and pulmonary vasculitis

1990 • 67 citations

A specific antagonist of platelet-activating factor suppresses oedema formation in an Arthus reaction but not oedema induced by leukocyte chemoattractants in rabbit skin.

1986 • 59 citations

Antioxidation theory of non-steroidal anti-inflammatory drugs based upon the inhibition of luminol-enhanced chemiluminescence from the myeloperoxidase reaction

1982 • 54 citations

The mechanism of Arthus reactions. II. The role of polymorphonuclear leucocytes and platelets in reversed passive reactions in the guinea-pig.

1955 • 44 citations

Selective inhibition of arachidonate 5‐lipoxygenase by novel acetohydroxamic acids: effects on acute inflammatory responses

1988 • 42 citations

Failure of the inhibition of rat gastric mucosal 5‐lipoxygenase by novel acetohydroxamic acids to prevent ethanol‐induced damage

1988 • 41 citations

The arthus reaction in rats, a possible test for anti-inflammatory and antirheumatic drugs

1979 • 33 citations

Effects of pharmacologic agents on the reversed passive Arthus reaction in the rat

1981 • 30 citations

Participation of superoxide anions at the prostaglandin phase of carrageenan foot-oedema.

1976 • 29 citations

Pharmacological profiles of a potential LTB4-antagonist, SM-9064

1986 • 25 citations

Therapeutic reduction of ongoing carrageenin-induced inflammation by lipoxygenase, but not cyclooxygenase inhibitors

1984 • 22 citations

Lipocortin

1989 • 22 citations

Modulation of acute immune complex-mediated tissue injury by the presence of polyionic substances.

1987 • 21 citations

Eicosanoids in Inflammatory Conditions of the Lung, Skin and Joints

1988 • 11 citations

The effects of anti-inflammatory and other agents on the rat dermal arthus reaction.

1982 • 11 citations

In vivo and in vitro assessment of the role of leukotriene B4 as a mediator of rat cutaneous late-phase reactions

1986 • 10 citations

Inhibition of 5-lipoxygenase: development of hydroxamic acids and hydroxyureas as potential therapeutic agents.

1991 • 3 citations