Integrated Next-Generation Sequencing and Avatar Mouse Models for Personalized Cancer Treatment

Hallmarks of Cancer: The Next Generation

2011 • 58,651 citations

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

2012 • 7,135 citations

Clonal evolution in cancer

2012 • 2,892 citations

Exploring the Genomes of Cancer Cells: Progress and Promise

2011 • 676 citations

Pilot Study Using Molecular Profiling of Patients' Tumors to Find Potential Targets and Select Treatments for Their Refractory Cancers

2010 • 596 citations

Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer

2011 • 470 citations

An In vivo Platform for Translational Drug Development in Pancreatic Cancer

2006 • 407 citations

A Pilot Clinical Study of Treatment Guided by Personalized Tumorgrafts in Patients with Advanced Cancer

2011 • 383 citations

The Genetic Basis for Cancer Treatment Decisions

2012 • 331 citations

KRAS mutation analysis: a comparison between primary tumours and matched liver metastases in 305 colorectal cancer patients

2011 • 279 citations

Personalizing Cancer Treatment in the Age of Global Genomic Analyses: PALB2 Gene Mutations and the Response to DNA Damaging Agents in Pancreatic Cancer

2010 • 243 citations

Clinical Implications of the Cancer Genome

2010 • 217 citations

Prognostic Significance of AKT/mTOR and MAPK Pathways and Antitumor Effect of mTOR Inhibitor in NF1-Related and Sporadic Malignant Peripheral Nerve Sheath Tumors

2012 • 128 citations

Finding the tumor copycat: Therapy fails, patients don't

2010 • 102 citations

Prioritizing Phase I Treatment Options Through Preclinical Testing on Personalized Tumorgraft

2011 • 85 citations

Making Personalized Cancer Medicine a Reality: Challenges and Opportunities in the Development of Biomarkers and Companion Diagnostics

2012 • 72 citations

Whole-Genome Sequencing: The New Standard of Care?

2012 • 66 citations

A feasibility and efficacy study of rapamycin and erlotinib for recurrent pediatric low‐grade glioma (LGG)

2012 • 58 citations

G-protein γ subunit GNG11 strongly regulates cellular senescence

2006 • 51 citations

Getting personalized cancer genome analysis into the clinic: the challenges in bioinformatics

2012 • 29 citations

Personalized Cancer Diagnostics

2011 • 27 citations

Exploring the cancer genome in the era of next-generation sequencing

2012 • 25 citations

The changes that count

2012 • 18 citations