Kinase activation and smooth muscle contraction in the presence and absence of calcium

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Direct activation of calcium-activated, phospholipid-dependent protein kinase by tumor-promoting phorbol esters.

1982 • 4,786 citations

Staurosporine, a potent inhibitor of phospholipidCa++dependent protein kinase

1986 • 2,445 citations

Protein kinase C in the regulation of smooth muscle contraction

1987 • 543 citations

Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells.

1986 • 491 citations

Cross-bridge phosphorylation and regulation of latch state in smooth muscle

1988 • 437 citations

TPA-induced contraction of isolated rabbit vascular smooth muscle

1984 • 266 citations

Vascular smooth muscle: The first recorded Ca2+ transients

1982 • 260 citations

Phorbol ester-induced contraction of arterial smooth muscle and inhibition of α-adrenergic response

1984 • 216 citations

Ca(2+)-independent isoforms of protein kinase C differentially translocate in smooth muscle

1992 • 185 citations

A novel mechanism for the Ca(2+)-sensitizing effect of protein kinase C on vascular smooth muscle: inhibition of myosin light chain phosphatase.

1994 • 182 citations

Phosphorylation of caldesmon in arterial smooth muscle

1989 • 165 citations

Protein kinase C of smooth muscle.

1992 • 154 citations

Phorbol ester-induced contraction in chemically skinned vascular smooth muscle

1986 • 154 citations

Caldesmon is a Ca2+-regulatory component of native smooth-muscle thin filaments

1985 • 148 citations

Regulation of myosin light chain and phosphorylase phosphorylation in tracheal smooth muscle.

1982 • 140 citations

Phosphorylation of smooth muscle caldesmon by mitogen-activated protein (MAP) kinase and expression of MAP kinase in differentiated smooth muscle cells

1992 • 131 citations

Carbachol induces a rapid and sustained hydrolysis of polyphosphoinositide in bovine tracheal smooth muscle measurements of the mass of polyphosphoinositides, 1,2-diacylglycerol, and phosphatidic acid.

1986 • 116 citations

Protein kinase C translocation in intact vascular smooth muscle strips

1990 • 112 citations

Effects of Ca2+ chelators on purified inositol 1,4,5-trisphosphate (InsP3) receptors and InsP3-stimulated Ca2+ mobilization

1993 • 110 citations

Endothelin-induced CA-independent contraction of the porcine coronary artery

1989 • 86 citations

Biochemical events associated with activation of smooth muscle contraction.

1988 • 83 citations

Dissociation of myosin phosphorylation and active tension during muscarinic stimulation of tracheal smooth muscle.

1987 • 78 citations

Cytoplasmic Ca2+ Is a Primary Determinant for Myosin Phosphorylation in Smooth Muscle Cells

1989 • 68 citations

Protein phosphorylation changes in bovine carotid artery smooth muscle during contraction and relaxation

1988 • 61 citations

Retraction

1991 • 60 citations

Measurement of cytoplasmic free Ca2+ concentration in rabbit aorta using the photoprotein, aequorin. Effect of atrial natriuretic peptide on agonist-induced Ca2+ signal generation.

1987 • 57 citations

Effects of inhibitors of protein kinase C and calpain in experimental delayed cerebral vasospasm

1992 • 55 citations

Phorbol 12,13-Diacetate-Induced Contraction of the Canine Basilar Artery: Role of Protein Kinase C

1991 • 49 citations

Endothelin stimulates a sustained 1,2-diacylglycerol increase and protein kinase C activation in bovine aortic smooth muscle cells

1989 • 47 citations

Mechanisms of Ca(2+)-independent contraction in single permeabilized ferret aorta cells.

1993 • 38 citations

Relation between Protein Kinase C and Calmodulin Systems in Cerebrovascular Contraction

1992 • 32 citations

Protein Kinase C: A Second E-C Coupling Pathway in Vascular Smooth Muscle?

1992 • 32 citations

Effects of myosin light-chain kinase inhibitor on catecholamine secretion from rat pheochromocytoma PC12h cells

1987 • 28 citations

Relation between Protein Kinase C and Calmodulin Systems in Cerebrovascular Contraction

1992 • 17 citations