Loss of spr-5 bypasses the requirement for the C.elegans presenilin sel-12 by derepressing hop-1

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Genomic sequencing.

1984 • 8,343 citations

Alzheimer's Disease: Genes, Proteins, and Therapy

2001 • 5,919 citations

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

1991 • 3,108 citations

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

2001 • 1,779 citations

Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans

2000 • 1,277 citations

Notch Signaling: From the Outside In

2000 • 958 citations

Prediction of the Coding Sequences of Unidentified Human Genes. IX. The Complete Sequences of 100 New cDNA Clones from Brain Which Can Code for Large Proteins in vitro

1998 • 848 citations

mut-7 of C. elegans, Required for Transposon Silencing and RNA Interference, Is a Homolog of Werner Syndrome Helicase and RNaseD

1999 • 745 citations

EGG-LAYING DEFECTIVE MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS

1983 • 730 citations

Nuclear Access and Action of Notch In Vivo

1998 • 730 citations

Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene

1995 • 705 citations

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex

1998 • 655 citations

Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders

2001 • 612 citations

The lin-12 locus specifies cell fates in caenorhabditis elegans

1983 • 598 citations

Regulation of Corepressor Function by Nuclear NADH

2002 • 595 citations

LIN-12/Notch signaling: lessons from worms and flies

1998 • 545 citations

CtBP, an Unconventional Transcriptional Corepressor in Development and Oncogenesis

2002 • 527 citations

CoREST is an integral component of the CoREST- human histone deacetylase complex

2001 • 484 citations

Regulation of Histone Acetylation and Transcription by INHAT, a Human Cellular Complex Containing the Set Oncoprotein

2001 • 469 citations

CoREST: A functional corepressor required for regulation of neural-specific gene expression

1999 • 467 citations

Regulation of Neuronal Traits by a Novel Transcriptional Complex

2001 • 418 citations

A global analysis of Caenorhabditis elegans operons

2002 • 359 citations

Biological roles and mechanistic actions of co-repressor complexes

2002 • 323 citations

Stable Histone Deacetylase Complexes Distinguished by the Presence of SANT Domain Proteins CoREST/kiaa0071 and Mta-L1

2001 • 323 citations

Operons in C. elegans: Polycistronic mRNA precursors are processed by trans-splicing of SL2 to downstream coding regions

1993 • 293 citations

Histone H3 Lysine 4 Methylation Disrupts Binding of Nucleosome Remodeling and Deacetylase (NuRD) Repressor Complex

2002 • 247 citations

CHE-3, a Cytosolic Dynein Heavy Chain, Is Required for Sensory Cilia Structure and Function in Caenorhabditis elegans

2000 • 209 citations

Human presenilin‐1, but not familial Alzheimer’s disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing

1997 • 201 citations

Protein Degradation: Four E3s For The Notch Pathway

2002 • 174 citations

A 30 Å long U-shaped catalytic tunnel in the crystal structure of polyamine oxidase

1999 • 163 citations

Formation of the vulva in Caenorhabditis elegans: a paradigm for organogenesis

1999 • 159 citations

Temporal reiteration of a precise gene expression pattern during nematode development.

1996 • 157 citations

HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling

1997 • 155 citations

FAD-containing polyamine oxidases: a timely challenge for researchers in biochemistry and physiology of plants

2001 • 135 citations

Chapter 33 Polyamine oxidase, properties and functions

1995 • 132 citations

Notch and Presenilin: a proteolytic mechanism emerges

2001 • 106 citations

RNA Interference Can Target Pre-mRNA: Consequences for Gene Expression in a Caenorhabditis elegans Operon

1999 • 105 citations

Ancient Roots Forced into Modern Pots

2002 • 96 citations

The Caenorhabditis elegans lin-12 gene mediates induction of ventral uterine specialization by the anchor cell

1995 • 96 citations

Organogenesis in C. elegans: Positioning of neurons and muscles in the egg-laying system

1990 • 87 citations

Reverse genetic analysis of Caenorhabditis elegans presenilins reveals redundant but unequal roles for sel- 12 and hop- 1 in Notch-pathway signaling

1999 • 80 citations

A second catalytic domain in the Elp3 histone acetyltransferases: a candidate for histone demethylase activity?

2002 • 79 citations

Identification of an FAD Superfamily Containing Protoporphyrinogen Oxidases, Monoamine Oxidases, and Phytoene Desaturase

1998 • 76 citations

Functional Requirement for Histone Deacetylase 1 in Caenorhabditis elegans Gonadogenesis

2002 • 74 citations

Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin

1998 • 63 citations

Structural Bases for Inhibitor Binding and Catalysis in Polyamine Oxidase^,

2001 • 63 citations

Genetic and phenotypic studies of hypomorphic lin-12 mutants in Caenorhabditis elegans.

1993 • 58 citations

spr-2 , a suppressor of the egg-laying defect caused by loss of sel-12 presenilin in Caenorhabditis elegans , is a member of the SET protein subfamily

2000 • 40 citations

The SEL-12 Presenilin Mediates Induction of the Caenorhabditis elegans Uterine π Cell Fate

2001 • 29 citations

REST Acts through Multiple Deacetylase Complexes

2001 • 24 citations

The Caenorhabditis elegans Presenilin sel-12 Is Required for Mesodermal Patterning and Muscle Function

2002 • 16 citations

Deleted Work

1955 • 0 citations