Chemical Aspects of Penicillin Allergy

The Specificity of Serological Reactions

1945 • 1,104 citations

DETOXICATION MECHANISMS

1960 • 760 citations

Advances in Drug Research

1964 • 615 citations

Mechanism and Structure in Organic Chemistry.

1960 • 590 citations

Mechanism and Structure in Organic Chemistry

1973 • 438 citations

The chemistry of penicillin

1949 • 408 citations

Synthesis of Penicillin: 6-Aminopenicillanic Acid in Penicillin Fermentations

1959 • 385 citations

STUDIES ON THE MECHANISM OF THE FORMATION OF THE PENICILLIN ANTIGEN

1961 • 340 citations

Principles of Drug Action.

1969 • 316 citations

Advances in drug research

1966 • 253 citations

HYPERSENSITIVITY REACTIONS TO ANTIBACTERIAL DRUGS IN INFECTIOUS MONONUCLEOSIS

1967 • 240 citations

HYPERSENSITIVITY TO PENICILLENIC ACID DERIVATIVES IN HUMAN BEINGS WITH PENICILLIN ALLERGY

1962 • 226 citations

The Specificity of Serological Reactions.

1963 • 221 citations

STUDIES ON THE MECHANISM OF THE FORMATION OF THE PENICILLIN ANTIGEN

1960 • 166 citations

Topics in pharmaceutical sciences 1985

1987 • 165 citations

Penicillin Allergy: The Formation of the Penicilloyl Determinant

1965 • 159 citations

Annual Reports in Medicinal Chemistry, 1965.

1967 • 154 citations

Penicillin allergy and the heterogenous immune responses of man to benzylpenicillin.

1966 • 153 citations

THE PREPARATION AND SOME PROPERTIES OF PENICILLENIC ACID DERIVATIVES RELEVANT TO PENICILLIN HYPERSENSITIVITY

1962 • 130 citations

The immunogenicity of cephalosporin derivatives and their cross-reaction with penicillin.

1966 • 101 citations

SOME IMMUNOCHEMICAL PROPERTIES OF PENICILLENIC ACID

1960 • 96 citations

N(α-<scp>D</scp>-Penicilloyl) Amines as Univalent Hapten Inhibitors of Antibody-Dependent Allergic Reactions to Penicillin

1962 • 95 citations

Penicilloyl-Polylysine as an Intradermal Test of Penicillin Sensitivity

1964 • 93 citations

Cephalothin—A New Antibiotic

1964 • 92 citations

ALLERGENIC RESIDUES IN PENICILLINS

1967 • 88 citations

Anaphylactoid Reaction to an Initial Dose of Sodium Cephalothin

1965 • 85 citations

A PENICILLOYLATED PROTEIN IMPURITY AS A SOURCE OF ALLERGY TO BENZYLPENICILLIN AND 6-AMINOPENICILLANIC ACID

1967 • 80 citations

Studies on the epidemiology of adverse drug reactions. IV. The relationship of cephalothin and penicillin allergy.

1966 • 80 citations

Clinical Trial of Cephaloridine (Ceporin), a New Broad-spectrum Antibiotic Derived from Cephalosporin C

1964 • 79 citations

Common Antigenic Determinants of Penicillin G, Ampicillin and the Cephalosporins Demonstrated in Men

1968 • 78 citations

Immunochemical Mechanisms of Drug Allergy

1966 • 78 citations

CROSS-ALLERGENICITY OF PENICILLIN G AND RELATED SUBSTANCES

1962 • 73 citations

The specificity of hemagglutination reactions in human and experimental penicillin hypersensitivity

1964 • 73 citations

Deacetylcephalosporin C

1961 • 71 citations

Cross-Allergenicity of the Penicillins and the Cephalosporins

1967 • 70 citations

Detection of Penicillin Hypersensitivity With Penicilloyl-Polylysine

1963 • 70 citations

Studies on the formation of the penicillin antigen. II. Some reactions of d-benzylpenicillenic acid in aqueous solution at pH 7.5

1961 • 69 citations

Treatment of Infections in Man With Cephalothin

1964 • 69 citations

The Role of Penicilloylated Protein Impurities, Penicillin Polymers and Dimers in Penicillin Allergy (Part 1 of 2)

1968 • 66 citations

Results of comparative skin tests with penicilloyl-polylysine and penicillin in patients with penicillin allergy

1965 • 64 citations

STUDIES ON THE IMMUNOLOGICAL MECHANISMS OF PENICILLIN ALLERGY. II. ANTIGENIC SPECIFICITIES OF ALLERGIC WHEAL-AND-FLARE SKIN RESPONSES IN PATIENTS WITH HISTORIES OF PENICILLIN ALLERGY.

1964 • 64 citations

A New Chemical Aspect of Penicillin Allergy: The Direct Reaction of Penicillin with ɛ-Amino-Groups

1965 • 64 citations

Clinical Detection of the Potential Allergic Reactor to Penicillin by Immunologic Tests

1966 • 60 citations

Immunological Diseases.

1966 • 60 citations

Experiences with Cephalothin

1966 • 58 citations

Catalytic Effect of Buffers on Degradation of Penicillin G in Aqueous Solution

1965 • 58 citations

Some Novel Acid-stable Penicillins

1961 • 58 citations

Studies on Penicillin Hypersensitivity

1962 • 56 citations

Ionisation Constants of Some Penicillins and of their Alkaline and Penicillinase Hydrolysis Products

1963 • 55 citations

STUDIES OF HYPERSENSITIVITY TO LOW MOLECULAR WEIGHT SUBSTANCES

1953 • 55 citations

Recent Clinical and Immunological Aspects of Penicillin Allergy (Part 1 of 2)

1965 • 54 citations

CEPHALOTHIN IN THE TREATMENT OF PENICILLIN SENSITIVE PATIENTS

1967 • 54 citations

Common Antigenic Determinants of Penicillin G, Cephalothin and 6-Aminopenicillanic Acid in Rabbits

1965 • 53 citations

Antigenic specificities of skin-sensitizing antibodies in sera from patients with immediate systemic allergic reactions to penicillin

1964 • 51 citations

Anaphylaxis to Cephalothin in a Patient Allergic to Penicillin

1968 • 50 citations

STUDIES ON THE DIMENSIONS OF THE RABBIT ANTI-BENZYLPENICILLOYL ANTIBODY-COMBINING SITES

1963 • 48 citations

STUDIES IN HUMAN PENICILLIN ALLERGY: A COMPARISON OF VARIOUS PENICILLOYL-POLYLYSINES.

1963 • 47 citations

Immunological Cross-reactivities of Cephalothin and its Related Compounds with Benzylpenicillin (Penicillin G)

1966 • 46 citations

Mechanism of Degradation of Penicillin G in Acidic solution

1965 • 45 citations

922. Cephalosporanic acids. Part II. Displacement of the acetoxy-group by nucleophiles

1965 • 45 citations

The reaction of benzylpenicillin with carbohydrates at neutral pH with a note on the immunogenicity of hapten polysaccharide conjugates

1967 • 45 citations

Degradation of Benzylpenicillin at pH 7.5 to D-Benzylpenicilloic Acid

1960 • 44 citations

CUTANEOUS SENSITIVITY TO PURIFIED BENZYLPENICILLIN

1967 • 42 citations

Poly-6-Aminopenicillanic Acid

1962 • 41 citations

Cephalothin Reaction After Penicillin Sensitization

1966 • 41 citations

Metabolism of oral cephalothin and related cephalosporins in the rat

1967 • 39 citations

Studies on the Epidemiology of Adverse Drug Reactions

1966 • 39 citations

Immunologic Responsiveness of Man to Penicillin

1963 • 39 citations

STUDIES ON THE IMMUNOLOGICAL MECHANISMS OF PENICILLIN ALLERGY. I. ANTIGENIC SPECIFICITIES OF GUINEA-PIG SKIN SENSITIZING RABBIT ANTI-BENZYLPENICILLIN ANTIBODIES.

1964 • 38 citations

Complexation of penicillins and penicilloic acids by cupric ion

1966 • 37 citations

Chemische Aspekte der Penicillin‐Allergie: Die direkte Penicilloylierung von ϵ‐Aminogruppen durch Penicilline bei pH 7, 4

1966 • 37 citations

Studies on Penicillin Hypersensitivity

1962 • 36 citations

Degradation kinetics of 6-aminopenicillanic acid

1967 • 35 citations

Unterscheidung der Penicilloinsäuren von funktionellen Derivaten ihrer. α‐Carboxylgruppe mittels Penamaldat‐Stabilitätsbestimmung

1966 • 34 citations

Association of hemagglutinating antibodies with skin sensitivity in penicillin allergy

1963 • 33 citations

REACTION OF 6-AMINOPENICILLANIC ACID WITH CARBON DIOXIDE

1961 • 33 citations

The cephalosporin C group

1967 • 28 citations

The Preparation of Penicilloyl-Polylysines, Skin Test Reagents for the Clinical Evaluation of Penicillin Hypersensitivity

1964 • 27 citations

Treatment of Bacterial Endocarditis with Cephalosporin Derivatives in Penicillin-Allergic Patients

1966 • 26 citations

Immune Cross-reactivity of Penicillin and Cephalothin

1967 • 26 citations

Formation of D-Penicillamine-Cysteine Mixed Disulphide by Reaction of D-Benzylpenicilloic Acid with Cystine

1960 • 26 citations

Kinetics of Reactions Involved in Penicillin Allergy I

1966 • 26 citations

Systemic Manifestations after a Skin Test with Penicilloyl-Polylysine

1964 • 24 citations

The mechanism of inactivation of penicillin by cysteine and other mercaptoamines

1960 • 24 citations

Stability of Potassium Phenethicillin I.

1962 • 23 citations

Immunologic response of rabbits to 6-aminopenicillanic acid

1961 • 23 citations

Stability of Methicillin

1965 • 22 citations

Antigenicity of Hapten Conjugates of Poly-D-lysine and of Poly-L-lysine in Strain 2 Guinea Pigs

1964 • 22 citations

Reactions of 6-aminopenicillanic acid with carbohydrates and related substances

1964 • 22 citations

Anaphylaxis to Cephaloridine in a Nurse Who Prepared Solutions of the Drug

1967 • 22 citations

Immunological Priming without Production of Circulating Bacterial Antibodies conditioned by Endotoxin and its Lipoid A Component

1966 • 21 citations

6-Aminopenicillanic Acid in Urine after Oral Administration of Penicillins

1960 • 20 citations

Zur Kenntnis der Benzylpenicilloinsäure

1967 • 18 citations

SEARCH FOR PROTEIN CONTAMINANTS IN BENZYLPENICILLIN

1968 • 16 citations

THE IMMUNOGENICITY OF HAPTEN-POLYLYSINE CONJUGATES. A COMPARISON OF D AND L POLYMERS.

1965 • 15 citations

Penicilloyl-Polylysine Skin Test:

1966 • 15 citations

1296. Cephalosporanic acids. Part III. Reactions with pyridine–kinetics and mechanism

1965 • 15 citations

Allergy to Phenethicillin

1960 • 14 citations

Studies on Antigenicity. The Effect of Succinylation of e-amino Groups on Antigenicity of Benzylpenicilloyl-Poly-L-Lysine Conjugates in Random-Bred and in Strain 2 Guinea Pigs.

1964 • 14 citations

Identification of p-Hydroxyphenoxymethyl Penicillin as a Metabolite of Phenoxymethyl Penicillin

1963 • 14 citations

Penicillin-Like Substances in Preparations of 6-Aminopenicillanic Acid

1962 • 13 citations

The Role of Penicillenic Acid and Penicillamine in Contact-Type Sensitivity to Penicillin

1963 • 13 citations

Antigenicity and cross-reactivity of 6-aminopenicillanic acid and penicillin G

1963 • 12 citations

Serum Copper Alteration after Ingestion of an Oral Contraceptive

1968 • 12 citations

Aminolysis of Benzylpenicillin by Aliphatic Diamines

1968 • 12 citations

Hematuria associated with methicillin therapy

1967 • 12 citations

THE BIOCHEMICAL BASIS OF AN ALLERGIC DRUG RESPONSE

1965 • 11 citations

Isomerization and Decomposition Products of Methicillin¹

1964 • 11 citations

Selective Suppression of Penicillin Hypersensitivity by Certain Phenoxy Propanediols

1967 • 11 citations

Catalysis by poly-L-lysine of aminolysis of penicillin by tris(hydroxymethyl)aminomethane

1969 • 11 citations

Chemische Aspekte der Penicillin‐Allergie: die direkte Bildung der Penicilloyl‐Determinanten aus Penicillin

1966 • 10 citations

The Immunogenicity of Hapten-Polylysine Conjugates

1965 • 10 citations

Formation of 6-Aminopenicillanic Acid by Alkaline Hydrolysis of Penicillins

1962 • 8 citations

Absorption, Metabolism, and Excretion of the Semisynthetic Penicillin 6-(2-Ethoxy-l-naphthamido)penicillanic Acid (Nafcillin)

1963 • 8 citations

Allergy to Antibiotics

1968 • 5 citations

Penicillin Sensitivity

1965 • 3 citations

The Role of Penicillenic Acid as an Antigenic Determinant in Immediate-Type Sensitivity to Penicillin

1963 • 3 citations

[Chemical study of phenoxymethyl penicillin. II. Formation and characteristics of phenoxymethylpenilloin acid].

1957 • 1 citations