The role of chemotherapy in the current treatment of gastric cancer

Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer.

1997 • 875 citations

Randomized comparison between chemotherapy plus best supportive care with best supportive care in advanced gastric cancer

1997 • 843 citations

Randomised comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) plus supportive care with supportive care alone in patients with non-resectable gastric cancer

1995 • 796 citations

Modified therapy with 5-fluorouracil, doxorubicin, and methotrexate in advanced gastric cancer

1993 • 787 citations

Late phase II study of novel oral fluoropyrimidine anticancer drug S-1 (1M tegafur–0.4M gimestat–1M otastat potassium) in advanced gastric cancer patients

1998 • 565 citations

Adjuvant therapy after curative resection for gastric cancer: meta-analysis of randomized trials.

1993 • 560 citations

Final Results of a Randomized Phase III Trial of Sequential High-Dose Methotrexate, Fluorouracil, and Doxorubicin Versus Etoposide, Leucovorin, and Fluorouracil Versus Infusional Fluorouracil and Cisplatin in Advanced Gastric Cancer: A Trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group

2000 • 536 citations

Sequential high-dose methotrexate and fluorouracil combined with doxorubicin--a step ahead in the treatment of advanced gastric cancer: a trial of the European Organization for Research and Treatment of Cancer Gastrointestinal Tract Cooperative Group.

1991 • 394 citations

A phase III randomized study of 5-fluorouracil and cisplatin versus 5-fluorouracil, doxorubicin, and mitomycin C versus 5-fluorouracil alone in the treatment of advanced gastric cancer

1993 • 360 citations

First demonstration of anti-lymphoma activity of BCL-2 antisense molecule-G3139; Results of phase I/IIA clinical trial

1997 • 320 citations

FAMTX versus etoposide, doxorubicin, and cisplatin: a random assignment trial in gastric cancer.

1992 • 293 citations

Phase II Study of a Combination of Irinotecan and Cisplatin Against Metastatic Gastric Cancer

1999 • 272 citations

Docetaxel (TaxotereTM) in advanced gastric cancer: results of a phase II clinical trial. EORTC Early Clinical Trials Group

1994 • 224 citations

Docetaxel (Taxotere®)-cisplatin (TC): An effective drug combination in gastric carcinoma

2000 • 206 citations

Phase II trial of docetaxel (Taxotere) in patients with adenocarcinoma of the upper gastrointestinal tract previously untreated with cytotoxic chemotherapy: the Eastern Cooperative Oncology Group (ECOG) Results of Protocol E1293

1996 • 203 citations

Laparoscopy, ultrasound and computed tomography in cancer of the oesophagus and gastric cardia: A prospective comparison for detecting intra-abdominal metastases

1989 • 190 citations

[Late phase II study of irinotecan hydrochloride (CPT-11) in advanced gastric cancer. CPT-11 Gastrointestinal Cancer Study Group].

1994 • 171 citations

Combination chemotherapy with docetaxel and cisplatin for locally advanced and metastatic gastric cancer

2001 • 170 citations

Phase I-II study of irinotecan hydrochloride combined with cisplatin in patients with advanced gastric cancer.

1997 • 139 citations

Paclitaxel, 5-fluorouracil, and cisplatin combination chemotherapy for the treatment of advanced gastric carcinoma

1999 • 133 citations

[Late phase II clinical study of RP56976 (docetaxel) in patients with advanced/recurrent gastric cancer: a Japanese Cooperative Study Group trial (group A)].

1998 • 90 citations

Phase II Trial of the Combination of Paclitaxel and 5-Fluorouracil in the Treatment of Advanced Gastric Cancer

1999 • 88 citations

Oral DPD-inhibitory fluoropyrimidine drugs.

2000 • 54 citations

Developments in the treatment of gastric cancer in Europe.

2000 • 40 citations

Phase II Trial of Outpatient Schedule of Paclitaxel in Patients with Previously Untreated Metastatic, Measurable Adenocarcinoma of the Stomach

2001 • 31 citations

Paclitaxel and weekly 24-hour infusion of 5-fluorouracil/folinic acid in advanced gastric cancer.

1997 • 30 citations

Preliminary study of fortnightly irinotecan hydrochloride plus cisplatin therapy in patients with advanced gastric and colorectal cancer

2001 • 26 citations

Results of a randomised trial comparing ECF with MCF in advanced oesophago-gastric cancer

1999 • 23 citations

Paclitaxel in the treatment of patients with upper gastrointestinal carcinomas.

1996 • 14 citations

Clinical trials for advanced gastrointestinal cancers in Japan

1998 • 9 citations

Clinical advances with topoisomerase I inhibitors in gastrointestinal malignancies

1999 • 9 citations

Advances in the therapy of gastric cancer

2002 • 9 citations

[Recent advances in chemotherapy for advanced gastric cancer: from the standpoint of survival advantages].

1995 • 4 citations

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