Differential effects of growth factor antagonists on neoplastic and normal prostatic cells

[105] Determination of DNA concentration with diphenylamine

1968 • 1,300 citations

Tumor Angiogenesis

1985 • 1,038 citations

Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis.

1988 • 647 citations

Protamine is an inhibitor of angiogenesis

1982 • 582 citations

Estrogenic Regulation of Growth and Polypeptide Growth Factor Secretion in Human Breast Carcinoma

1987 • 576 citations

Suramin Protection of T Cells in Vitro Against Infectivity and Cytopathic Effect of HTLV-III

1984 • 396 citations

Suramin inhibition of growth factor receptor binding and mitogenicity in AKR‐2B cells

1987 • 387 citations

Adaptation versus selection as the mechanism responsible for the relapse of prostatic cancer to androgen ablation therapy as studied in the Dunning R-3327-H adenocarcinoma.

1981 • 382 citations

Suramin: an anticancer drug with a unique mechanism of action.

1989 • 370 citations

Goodman and Gilman's The Pharmacological Basis of Therapeutics.

1981 • 339 citations

Direct mitogenic effects of insulin, epidermal growth factor, glucocorticoid, cholera toxin, unknown pituitary factors and possibly prolactin, but not androgen, on normal rat prostate epithelial cells in serum-free, primary cell culture.

1984 • 315 citations

Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin.

1986 • 270 citations

Relationship between DNA fragmentation and apoptosis in the programmed cell death in the rat prostate following castration

1989 • 266 citations

Polymerization of deoxyribonucleotides in relation to androgen-induced prostatic growth

1968 • 208 citations

Role of transforming growth factor ‐α in human prostate cancer cell growth

1989 • 142 citations

The Influence of Hormonal Therapy on Survival of Men with Advanced Prostatic Cancer

1982 • 141 citations

Role of epithelial-stromal interactions in the control of gene expression in the prostate: An hypothesis

1986 • 116 citations

Non-hormone chemotherapy for prostate cancer: principles of treatment and application to the testing of new drugs.

1988 • 111 citations

Quantal relationship between prostatic dihydrotestosterone and prostatic cell content: Critical threshold concept

1987 • 90 citations

Protamine sulfate inhibits mitogenic activities of the extracellular matrix and fibroblast growth factor, but potentiates that of epidermal growth factor

1987 • 86 citations

Expression of basic fibroblast growth factor mRNA in benign prostatic hyperplasia and prostatic carcinoma

1988 • 80 citations

Development and characteristics of the available animal model systems for the study of prostatic cancer.

1987 • 72 citations

Gene activity during the early phase of androgen-stimulated rat prostate regrowth.

1989 • 72 citations

Heparin binding affinity of rat prostatic growth factor in normal and cancerous prostates: partial purification and characterization of rat prostatic growth factor in the Dunning tumor.

1987 • 71 citations

Comparative analysis of growth factors in normal and pathologic human prostates

1988 • 47 citations

Quantification of Suramin by Reverse-Phase Ion-Pairing High-Performance Liquid Chromatography

1985 • 44 citations

Effects of Suramin on the Function and Structure of the Adrenal Cortex in the Cynomolgus Monkey

1987 • 41 citations

Protamine inhibits platelet derived growth factor receptor activity but not epidermal growth factor activity

1984 • 36 citations

The Inhibition of Human Adrenal Steroidogenic Enzyme Activities by Suramin*

1989 • 28 citations

New model for studying the effects of cancer chemotherapeutic agents on the growth of the prostate gland

1975 • 19 citations