Use of live attenuated bacteria to stimulate immunity

Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines

1981 • 2,042 citations

Actions of cholera toxin and the prevention and treatment of cholera

1981 • 532 citations

Cistrons encoding Escherichia coli heat-labile toxin

1979 • 273 citations

Immune Response to Cholera Toxin Epitope Inserted in Salmonella Flagellin

1989 • 257 citations

Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues

1989 • 252 citations

Characterization of porin and ompR mutants of a virulent strain of Salmonella typhimurium: ompR mutants are attenuated in vivo

1989 • 236 citations

Molecular cloning and characterization of protective outer membrane protein P.69 from Bordetella pertussis.

1989 • 170 citations

Structure of tetanus toxin. I. Breakdown of the toxin molecule and discrimination between polypeptide fragments.

1977 • 163 citations

Protective immunity evoked by oral administration of attenuated aroA Salmonella typhimurium expressing cloned streptococcal M protein.

1988 • 141 citations

Oral vaccination of mice against tetanus by use of a live attenuated Salmonella carrier

1990 • 113 citations

Construction and characterization in vivo of Bordetella pertussis aroA mutants

1990 • 100 citations

Construction and Characterization of Vaccine Strains of Salmonella Harboring Mutations in Two Different aro Genes

1988 • 91 citations

Stable expression of foreign antigens from the chromosome of Salmonella typhimurium vaccine strains

1990 • 79 citations

Isolation of orally attenuated Salmonella typhimurium following TnphoA mutagenesis

1989 • 62 citations

Virulence, persistence, and immunogenicity of Yersinia enterocolitica O:8 aroA mutants

1989 • 60 citations

Cloning and nucleotide sequence of the aroA gene of Bordetella pertussis

1988 • 56 citations

Cloning and characterisation of the serC and aroA genes of Yersinia enterocolitica, and construction of an aroA mutant

1989 • 38 citations

Toxicity of papain-digested tetanus toxin. Pathological effect of fragment B in the absence of spastic paralysis.

1978 • 30 citations