The inductive effect of interleukin-4 on IgG4 and IgE synthesis in human peripheral blood lymphocytes

Interferon-γ and B Cell Stimulatory Factor-1 Reciprocally Regulate Ig Isotype Production

1987 • 1,936 citations

IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2.

1988 • 939 citations

Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities.

1986 • 529 citations

Isolation and characterization of a human interleukin cDNA clone, homologous to mouse B-cell stimulatory factor 1, that expresses B-cell- and T-cell-stimulating activities.

1986 • 514 citations

Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter

1986 • 480 citations

Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.

1987 • 449 citations

Evaluation of monoclonal antibodies having specificity for human IgG sub-classes: Results of an IUIS/WHO collaborative study

1985 • 393 citations

Differential regulation of IgG1 and IgE synthesis by interleukin 4.

1988 • 389 citations

Interleukin 4 causes isotype switching to IgE in T cell-stimulated clonal B cell cultures.

1988 • 359 citations

Induction of human IgE synthesis requires interleukin 4 and T/B cell interactions involving the T cell receptor/CD3 complex and MHC class II antigens.

1989 • 331 citations

IgE production by normal human B cells induced by alloreactive T cell clones is mediated by IL-4 and suppressed by IFN-gamma.

1988 • 315 citations

IFN-gamma stimulates IgG2a secretion by murine B cells stimulated with bacterial lipopolysaccharide.

1988 • 308 citations

Interleukin 4 induces synthesis of IgE and IgG4 in human B cells

1989 • 300 citations

IgG4 Antibodies in Egyptian Patients with Schistosomiasis

1981 • 133 citations

IgE responses in human filariasis. IV. Parallel antigen recognition by IgE and IgG4 subclass antibodies.

1986 • 129 citations

Human recombinant IL-4 induces activated B lymphocytes to produce IgG and IgM.

1988 • 119 citations

Effect of B cell stimulatory factor-1 (interleukin 4) on Fc epsilon and Fc gamma receptor expression on murine B lymphocytes and B cell lines.

1987 • 117 citations

Role of interleukins in induction and regulation of human IgE synthesis

1989 • 100 citations

Human recombinant interleukin 4 induces normal B cells to produce soluble CD23/IgE‐binding factor analogous to that spontaneously released by lymphoblastoid B cell lines

1988 • 76 citations

Human IgE synthesis in vitro: a reassessment.

1981 • 70 citations

ELISA measurement of IgG subclass production in culture supernatants using monoclonal antibodies

1987 • 47 citations

In vitro synthesis of IgE by human peripheral blood leucocytes. III. Release of pre-formed antibody.

1983 • 46 citations

Effect of recombinant human interleukin 4 on spontaneous in vitro human IgE synthesis^*

1988 • 41 citations

Increase of precursor frequency and clonal size of murine IgE-secreting cells by IL-4.

1988 • 36 citations

Development of hypogammaglobulinaemia in a patient with common variable immunodeficiency

1989 • 25 citations

Immunoglobulin subclass distribution of specific antibodies in allergic patients

1987 • 25 citations