New DNA Technology and the DNA Biosensor

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Methods of Biochemical Analysis

1956 • 4,535 citations

ELECTRODE SYSTEMS FOR CONTINUOUS MONITORING IN CARDIOVASCULAR SURGERY

1962 • 3,599 citations

Molecular Biology of the Gene

1970 • 2,116 citations

A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane

1965 • 1,981 citations

Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes.

1981 • 1,165 citations

Rapid and sensitive colorimetric method for visualizing biotin-labeled DNA probes hybridized to DNA or RNA immobilized on nitrocellulose: Bio-blots.

1983 • 1,075 citations

Europium as a label in time-resolved immunofluorometric assays

1984 • 865 citations

Design of Sequence-Specific DNA-Binding Molecules

1986 • 840 citations

Positive identification of an immigration test-case using human DNA fingerprints

1985 • 593 citations

Non-radioactive hybridization probes prepared by the chemical labelling of DNA and RNA with a novel reagent, photobiotin

1985 • 526 citations

Field effect transistor sensitive to penicillin

1980 • 496 citations

Molecular biology of the gene

1988 • 332 citations

A colorimetric method for DNA hybridization

1984 • 292 citations

Enzyme-immunoassay.

1976 • 289 citations

Branched DNA molecules: Intermediates in T4 recombination

1971 • 244 citations

Chemilunimescence of Luminol: The Chemcial Reaction

1964 • 223 citations

2-Acetylaminofluorene-modified probes for the indirect hybridocytochemical detection of specific nucleic acid sequences

1984 • 208 citations

Fluorescent excitation transfer immunoassay. A general method for determination of antigens.

1976 • 207 citations

Chemically modified nucleic acids as immunodetectable probes in hybridization experiments.

1984 • 202 citations

An immunospecific microbalance

1972 • 202 citations

Piezoelectric immuno sensor for the detection of candida albicans microbes

1986 • 199 citations

Bioluminescence Assay: Principles and Practice

1968 • 185 citations

Sandwich hybridization as a convenient method for the detection of nucleic acids in crude samples

1983 • 172 citations

A novel method to map transcripts: Evidence for homology between an adenovirus mRNA and discrete multiple regions of the viral genome

1977 • 165 citations

Nucleic Acid Guanine: Reaction with the Carcinogen N -Acetoxy-2-Acetylaminofluorene

1966 • 151 citations

Chemiluminescence fiber optic probe for hydrogen peroxide based on the luminol reaction

1978 • 136 citations

A new method of in situ hybridization

1975 • 110 citations

Opto-electronic immunosensors: A review of optical immunoassay at continuous surfaces

1985 • 105 citations

Human genetic diseases : a practical approach

1986 • 102 citations

Quick-Blot: Selective mRNA or DNA Immobilization from Whole Cells

1983 • 97 citations

NOVEL TEST FOR RAPID VIRAL DIAGNOSIS: DETECTION OF ADENOVIRUS IN NASOPHARYNGEAL MUCUS ASPIRATES BY MEANS OF NUCLEIC-ACID SANDWICH HYBRIDISATION

1983 • 97 citations

Time-resolved fluorometry: a sensitive method to quantify DNA-hybrids

1986 • 80 citations

Principles of Genetic Engineering

2020 • 63 citations

Photovoltaic Determination of Hydrogen Peroxide with A Biophotodiode

1984 • 59 citations

Science and technology in Japan

1985 • 44 citations

A rapid method of gene detection using DNA bound to Sephacryl

1985 • 44 citations

An electrochemical assay system for peroxidase and peroxidase-couplers reactions based on a fluoride ion-selective electrode.

1982 • 41 citations

Studies in peroxidase action. Part IX. Reactions involving the rupture of the C–F, C–Br, and C–I links in aromatic amines

1954 • 38 citations

Human genetic diseases — A practical approach

1987 • 35 citations

Nonisotopic detection methods for strand displacement assays of nucleic acids.

1986 • 35 citations

Novel immunosensors

1986 • 33 citations

Strand displacement applied to assays with nucleic acid probes.

1986 • 31 citations

Strand displacement applied to assays with nucleic acid probes.

1986 • 28 citations

A versatile method for the coupling of protein to DNA: synthesls of αγ Marcroglobulin-Dna conjugates

1983 • 24 citations

Pushing Probes to Market

1987 • 21 citations

A simple and sensitive method for detection of nucleic acids fixed on nylon-based filters

1986 • 19 citations

TPNH-cytochrome c reductase and nitrate reductase in mutant and wild type Neurospora and Aspergillus

1963 • 18 citations

Non-Electrode Biosensors in Clinical Biochemistry

1985 • 17 citations

Conformational changes in DNA induced by its adsorption at negatively charged surfaces

1983 • 13 citations

A simple and efficient enzymatic method for covalent attachment of DNA to cellulose. Application for hybridization-restriction analysis and for in vitro synthesis of DNA probes

1986 • 13 citations

Analytical Uses of Immobilized Enzymes

1982 • 12 citations

EFFECTIVE STRESS AND SOIL CONSTANTS OF UNSATURATED KAOLINE

1986 • 11 citations