Selection of dual Vα T cells

Expression of Two T Cell Receptor α Chains: Dual Receptor T Cells

1993 • 527 citations

In transgenic mice the introduced functional T cell receptor β gene prevents expression of endogenous β genes

1988 • 374 citations

Lymphoid Development in Mice Congenitally Lacking T Cell Receptor αβ-Expressing Cells

1992 • 371 citations

Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen.

1994 • 353 citations

Exclusion and inclusion of α and β T cell receptor alleles

1992 • 346 citations

T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide: implications for T cell allelic exclusion and antigen-specific repertoire.

1991 • 323 citations

Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes.

1993 • 247 citations

A T cell clone expresses two T cell receptor α genes but uses one αβ heterodimer for allorecognition and self MHC-restricted antigen recognition

1988 • 200 citations

Engagement of the T-cell receptor during positive selection in the thymus down-regulates RAG-1 expression.

1992 • 152 citations

Expression of two T cell receptor α chains on the surface of normal murine T cells

1995 • 131 citations

Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector function.

1996 • 121 citations

The joining of germ-line Vα to Jα genes replaces the preexisting Vα-Jα complexes in a T cell receptor α,β positive T cell line

1988 • 87 citations

Dual T cell receptor alpha chain T cells in autoimmunity.

1995 • 82 citations

T cell depletion in transgenic mice carrying a mutant gene for TCR-β

1989 • 77 citations

Novel post-translational regulation of TCR expression in CD4+CD8+ thymocytes influenced by CD4

1990 • 67 citations

Each of the two productive T cell receptor α-gene rearrangements found in both the A10 and BM 3.3 T cell clones give rise to an α chain which can contribute to the constitution of a surface-expressed αβ dimer

1991 • 59 citations

Allelic exclusion of mouse T cell receptor α chains occurs at the time of thymocyte TCR up-regulation

1995 • 48 citations

The influence of positive selection on RAG expression in thymocytes

1995 • 46 citations

Post-translational attainment of allelic exclusion of the T cell receptor α chain in a T cell clone

1991 • 43 citations

Post-transcriptional allelic exclusion of two functionally rearranged T cell receptor α genes

1989 • 29 citations

Allelic exclusion of α chains in TCRs

1994 • 26 citations

Non‐obese diabetic mice hemizygous at the T cell receptor α locus are susceptible to diabetes and sialitis

1996 • 25 citations