Modification of the essential amino acids of human pancreatic carboxylic-ester hydrolase

Role of a Buried Acid Group in the Mechanism of Action of Chymotrypsin

1969 • 1,060 citations

[41] Modification of histidyl residues in proteins by diethylpyrocarbonate

1977 • 813 citations

Phospholipase A2 and its zymogen from porcine pancreas. VI. Histidine at the active site of phospholipase A2

1974 • 465 citations

Ethoxyformylation of proteins. Reaction of ethoxyformic anhydride with .alpha.-chymotrypsin, pepsin, and pancreatic ribonuclease at pH 4

1970 • 388 citations

The Kinetics of the α-Chymotrypsin-Catalyzed Hydrolysis of p-Nitrophenyl Acetate^*

1962 • 260 citations

Evidence of an essential histidine residue in thermolysin

1974 • 210 citations

Studies on the substrate specificity of a carboxyl ester hydrolase from human pancreatic juice. II. Action on cholesterol esters and lipid-soluble vitamin esters

1980 • 186 citations

Purification and characterization of a carboxyl ester hydrolase from human pancreatic juice

1978 • 148 citations

Modification of carboxyl groups in bovine carboxypeptidase A. I. Inactivation of the enzyme by N-ethyl-5-phenylisoxazolium-3'-sulfonate (Woodward's reagent K)

1971 • 98 citations

Pig liver esterase. Reactions with alcohols, structure-reactivity correlations, and acyl-enzyme intermediate

1971 • 98 citations

Carboxyl Group Modification and the Activity of Lysozyme

1969 • 87 citations

Mechanism of pancreatic lipase action. 2. Catalytic properties of modified lipases

1976 • 86 citations

Methylation of histidine-57 in α-chymotrypsin by methyl ρ-nitrobenzenesulfonate. New approach to enzyme modification

1970 • 82 citations

p-Nitrophenylacetate as a Substrate for a Carboxyl-ester Hydrolase in Pancreatic Juice and Intestinal Content

1970 • 81 citations

Effect of alcohols on the hydrolysis catalyzed by human pancreatic carboxylic-ester hydrolase

1981 • 76 citations

Isolation of acetyl peptides from acetylchymotrypsin

1958 • 67 citations

The Number of Catalytically Essential Carboxyl Groups in Pepsin

1972 • 59 citations

On the homology of the active-site peptides of liver carboxylesterases

1969 • 53 citations

On the active site of horse-liver ali esterase II. Amino acid sequence in the DFP-binding site of the enzyme

1959 • 51 citations

Purification and Properties of Rat Liver Microsomal Esterases

1974 • 46 citations

On the active site of horse-liver ali esterase I. Reaction of the enzyme with diisopropylphosphorofluoridate

1959 • 40 citations

Essential Histidyl Residues of Octopine Dehydrogenase

1971 • 39 citations

An essential carboxylic acid group in human prostate acid phosphatase

1979 • 37 citations

Structure and Conformation of Human Pancreatic Carboxyl-Ester Hydrolase

1981 • 37 citations

Esterification of cholesterol and lipid-soluble vitamins by human pancreatic carboxyl ester hydrolase

1980 • 32 citations

Binding of human pancreatic carboxylic ester hydrolase to lipid interfaces

1981 • 25 citations

The reactivity of carboxyl groups in chymotrypsinogen

1969 • 19 citations

Effects of Alcohols on Hydrolysis Catalyzed by Beef‐Liver Esterase

1972 • 16 citations

The involvement of histidine in the action of liver carboxylesterases

1973 • 15 citations

Isolation of a specific acyl-chymotrypsin intermediate

1966 • 13 citations

Dependence on pH of the activity of pig liver esterase

1980 • 13 citations

Untersuchungen zur Photooxydation von Schweineleberesterase

1969 • 13 citations

The role of carboxyl groups in the activity of pancreatic lipase

1973 • 11 citations

Is histidine involved in the catalytic mechanism of unspecific carboxylesterases?

1975 • 4 citations